Results 41 to 50 of about 111,541 (269)

The Beauty of the Fragment Reconstituted in the Great Wall

International Journal of Film and Media Arts, 2021
Max Hattler’s short abstract animations demonstrate an awareness of the form’s historic 1920’s European Abstract Animation precedents, is informed by the structurally focused minimalism of the 60’s and re-tools pre-cinema toys. Yet his work speaks to the
Dirk De Bruyn
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Application of Wake Characteristics to Prediction of Broadband Noise of a Multiblade Fan

Journal of Fluid Science and Technology, 2008
In this study, the wake characteristics of an arc blade were measured by the wind tunnel experiment; the characteristics were defined as the width of the wake, diameter of the vortex, ratio of the vortex scale, and the local lift.
Soichi SASAKI, Hidechito HAYASHI
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Investigation of Interaction between Vortices and Cavitation in a Turbulent Shear Layer

Journal of Fluid Science and Technology, 2011
We performed numerical simulations of a non-steady separated shear layer with and without cavitation to examine the effect on flow dynamics. Particular focus was given to the interaction between vortices and cavitation. In the simulations, streamwise and
Takashi OHTA, Hiroki SAKAI, Kie OKABAYASHI, Takeo KAJISHIMA   +3 more
doaj   +1 more source

Vortex holography [PDF]

Nuclear Physics B, 2002
We show that the Abelian Higgs field equations in the four dimensional anti de Sitter spacetime have a vortex line solution. This solution, which has cylindrical symmetry in AdS$_4$, is a generalization of the flat spacetime Nielsen-Olesen string. We show that the vortex induces a deficit angle in the AdS$_4$ spacetime that is proportional to its mass ...
Dehghani, M. H., Ghezelbash, A. M., Mann, R. B.   +2 more
openaire   +3 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Wavelet multi-resolution analysis on wake flows behind three-dimensional bluff bodies

Journal of Fluid Science and Technology, 2015
In order to improve the aerodynamic performance of external side mirror of race car, the wake flow around three-dimensional bluff body is studied in this study.
Shun FUJIMOTO, Akira RINOSHIKA
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

3D-Printed SMC Core Alternators: Enhancing the Efficiency of Vortex-Induced Vibration (VIV) Bladeless Wind Turbines

Applied Sciences
This study investigates the application of soft magnetic composite (SMC) materials in alternator core manufacturing for bladeless wind turbines operating under the principle of vortex-induced vibration (VIV), employing additive manufacturing (AM ...
Enrique González-González, David J. Yáñez, Arturo Hidalgo, Susana Del Pozo, Susana Lagüela   +4 more
doaj   +1 more source