Results 51 to 60 of about 531,970 (297)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Serious game for cognitive assessment. Validation of a psychometric embedded test

International Journal of Serious Games
The evaluation of performance in serious video games is crucial when it comes to providing empirical evidence of the effectiveness of this type of educational tools.
Jorge Quimbaya, Alejandra Herrera, Cesar Mejia   +2 more
doaj   +1 more source

The Vortex Surface in a Three-Body Quantum System

Atoms, 2023
Vortices are structures known in our daily lives and observed in a wide variety of systems, from cosmic to microscopic scales. Relatively recent studies showed that vortices could also appear in simple quantum systems.
Tamara A. Guarda, Francisco Navarrete, Raúl O. Barrachina   +2 more
doaj   +1 more source

Vortex annihilation in the ordering kinetics of the O(2) model

, 1996
The vortex-vortex and vortex-antivortex correlation functions are determined for the two-dimensional O(2) model undergoing phase ordering. We find reasonably good agreement with simulation results for the vortex-vortex correlation function where there is
A. D. Rutenberg, A. J. Bray, A. J. Bray, A. J. Bray, A. J. Bray, A. J. Bray, B. Yurke, F. Liu, F. Liu, G. F. Mazenko, G. F. Mazenko, G. F. Mazenko, G. F. Mazenko, G. F. Mazenko, G. Porod, Gene F. Mazenko, H. Toyoki, M. Mondello, N. D. Mermin, nt. Near, R. A. Wickham, Robert A. Wickham, T. Nagaya   +22 more
core   +1 more source

Vortex Phases

, 2002
These lecture notes are meant to provide a pedagogical introduction, and present the latest theoretical and experimental developments on the physics of vortices in type II superconductors.
Giamarchi, T., Bhattacharya, S.
openaire   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Research on the Unsteady Flow and Vortex Characteristics of Cavitation at the Tongue in Centrifugal Pump [PDF]

Journal of Applied Fluid Mechanics
In order to study the unsteady flow and vortex characteristics of tongue cavitation, numerical calculation is carried out for the whole flow channel given different conditions. Then, the calculation results are verified experimentally.
Z. Y. Luo, Y. Feng, X. Y. Sun, Y. Gong, J. X. Lu, X. W. Zhang   +5 more
doaj   +1 more source

Standard and Modified SST Models with the Consideration of the Streamline Curvature for Separated Flow Calculation in a Narrow Channel with a Conical Dimple on the Heated Wall

Energies, 2021
The testing of the standard and modified SST models of the transfer of shear stresses was carried out on an example of calculating the heat transfer with an intense detached flow around a conical dimple with a slope angle of 45° on the heated wall of a ...
Sergey Isaev, Dmitry Nikushchenko, Alexandr Sudakov, Nikita Tryaskin, Ann Egorova, Leonid Iunakov, Alexandr Usachov, Valery Kharchenko   +7 more
doaj   +1 more source

Visualizing Pure Quantum Turbulence in Superfluid $^{3}$He: Andreev Reflection and its Spectral Properties [PDF]

, 2015
Superfluid $^3$He-B in the zero-temperature limit offers a unique means of studying quantum turbulence by the Andreev reflection of quasiparticle excitations by the vortex flow fields.
Baggaley, A. W., Barenghi, C. F., Fisher, S. N., Pickett, G. R., Sergeev, Y. A., Suramlishvili, N., Tsepelin, V.   +6 more
core   +3 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source