Results 61 to 70 of about 531,970 (297)
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Intrinsic and extrinsic vortex nucleation mechanisms in the flow [PDF]
, 1996 We propose very general vortex nucleation mechanisms analogous to a hydrodynamic instability and calculate associated critical velocity in agreement with experiments.
Kusmartsev, F. V.
core +2 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Applied SciencesThis study investigates the application of soft magnetic composite (SMC) materials in alternator core manufacturing for bladeless wind turbines operating under the principle of vortex-induced vibration (VIV), employing additive manufacturing (AM ...
Enrique González-González +4 more
doaj +1 more source
Paramagnetic Meissner effect in ZrB12 single crystal with non-monotonic vortex-vortex interactions
, 2017 The magnetic response related to paramagnetic Meissner effect (PME) is studied in a high quality single crystal ZrB12 with non-monotonic vortex-vortex interactions.
Filipov, Volodimir B. +6 more
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Effect of the Preheating Strategy on the Combustion Process of the Intake Manifold Burner
Applied Sciences, 2022 The intake air preheating is an effective method to improve the cold start performance of diesel engines. The combustion process and ignition probability were investigated in the present study.
Zhishuang Li, Ziman Wang, Haoyang Mo
doaj +1 more source
Collective Josephson vortex dynamics in a finite number of intrinsic Josephson junctions
, 2006 We report the experimental confirmation of the collective transverse plasma modes excited by the Josephson vortex lattice in stacks of intrinsic Josephson junctions in Bi$_{2}$Sr$_{2}$CaCu$_{2}$O$_{8+x}$ single crystals.
Bae, Myung-Ho +2 more
core +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Nanomaterials, 2022 Understanding the behaviour of vortices under nanoscale confinement in superconducting circuits is important for the development of superconducting electronics and quantum technologies.
Benjamin McNaughton +3 more
doaj +1 more source