Results 41 to 50 of about 44,596 (308)

Aerodynamically shaped vortex generators

open access: yesWind Energy, 2015
AbstractAn aerodynamically shaped vortex generator has been proposed, manufactured and tested in a wind tunnel. The effect on the overall performance when applied on a thick airfoil is an increased lift to drag ratio compared with standard vortex generators. Copyright © 2015 John Wiley & Sons, Ltd.
M. O. L. Hansen   +6 more
openaire   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Design and Development of Vortex Generators on Cylindrical Tower

open access: yesModelling and Simulation in Engineering
This work presents a numerical study on flow configurations and pressure distribution of cylindrical towers attached with different shapes of vortex generators.
Amnart Boonloi   +2 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

CFD (Computational Fluid Dynamics) Modeling on Narasena Bengawan UV Team Quickster UAV Wings with Addition of Vortex Generator to Aerodynamic Performance

open access: yesMekanika, 2021
This research is based on obtaining the best possible aerodynamic performance for the Quickster Narasena Bengawan UV Team UAV aircraft wing design. One of the factors that greatly affects the flying performance of a UAV is the wing.
Mohammad Fahmi Luthfi   +3 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

On singularity formation in three-dimensional vortex sheet evolution [PDF]

open access: yes, 1999
It is shown that if a doubly-infinite vortex sheet has cylindrical shape and strength distributions at some initial time, then this property is retained in its subsequent evolution.
Brady, M., Pullin, D. I.
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Coherent cross-talk and parametric driving of matter-wave vortices

open access: yes, 2011
We show that the interaction between vortices and sound waves in atomic Bose-Einstein condensates can be elucidated in a double-well trap: with one vortex in each well, the sound emitted by each precessing vortex can be driven into the opposing vortex ...
A. J. Allen   +5 more
core   +1 more source

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