Results 51 to 60 of about 6,790 (314)
Design and Development of Vortex Generators on Cylindrical Tower
Modelling and Simulation in EngineeringThis work presents a numerical study on flow configurations and pressure distribution of cylindrical towers attached with different shapes of vortex generators.
Amnart Boonloi +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
VORTEX BLADELESS TURBINE GYRO E-GENERATOR [PDF]
, 2018 <p>Vortex-Bladeless is a Spanish SME whose objective is to develop a new concept of wind turbine without blades called Vortex or vorticity wind turbine.
Prafull Navkar *1, Rushikesh Sable 2, Mayur Satputale
core +1 more source
Mekanika, 2021 This research is based on obtaining the best possible aerodynamic performance for the Quickster Narasena Bengawan UV Team UAV aircraft wing design. One of the factors that greatly affects the flying performance of a UAV is the wing.
Mohammad Fahmi Luthfi +3 more
doaj +1 more source
A generalization of vortex lines [PDF]
Journal of Geometry and Physics, 2018 8 pages, 3 figures; version to be published in Journal of Geometry and ...
openaire +2 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Double-branched vortex generator [PDF]
, 1985 In order to assess the suitability of using a double branched vortex generator in parametric studies involving vortex interactions, an experimental study of the main vortex and secondary flows produced by a double branched vortex generator was conducted ...
Mehta, R. D. +2 more
core +1 more source
Effect of Employing Vortex Generator on Curve Diffuser Performance [PDF]
, 2021 A diffuser is commonly applied in fluid-flow engineering applications with its simplest form of expanding area in the flow direction. A curve diffuser is one of its kinds often associated with secondary flow separation, thus improvement via installing ...
Hau, Chin Yong +6 more
core +1 more source