Results 121 to 130 of about 46,839 (349)
Advanced Science, EarlyView.A programmable passive digital shutter based on multiphase liquid–liquid interface dynamics is introduced for precise fabrication of hydrogel microfibers. By modulating the shutter operation, microfibers with tunable geometry—including linear, helical, tadpole‐like, and spherical forms—are produced.
Dongrui Zhang +14 more
wiley +1 more source
Advanced Science, EarlyView.Hydrogen voltage gated channel 1 (HVCN1) is upregulated in microglia of both ALS patients and its mouse model. HVCN1 deficiency enhances microglial migration via suppressing Akt signaling, promotes neurotrophic capacity and motor function, and prolongs survival of the SOD1G93A ALS mice. This study identifies HVCN1 as a novel, promising druggable target
Fan Wang +16 more
wiley +1 more source
The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia
Advanced Science, EarlyView.The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo +3 more
wiley +1 more source
Determination of object position, vortex shedding frequency and flow velocity using artificial lateral line canals [PDF]
, 2011 Adrian Klein, Horst Bleckmann
openalex +1 more source
Advanced Science, EarlyView.Multiomic profiling of HER2‐low breast cancer identifies three proteomic subtypes with distinct therapeutic strategies: endocrine, antiangiogenic, and anti‐HER2 therapies. Genomic and lactate modification landscapes are detailed, providing insights for precise management.
Shouping Xu +20 more
wiley +1 more source
The Interaction Vortex Flow Around Two Bluff Cylinders
EPJ Web of Conferences, 2013 In this study, the interaction vortex flow features around a pair of parallel arranged bluff cylinders were observed by visualizing water flow experiment at the range of the gap ratio G/d=0~3.
Hirao K., Yokoi Y.
doaj +1 more source
Effects of Streamlining a Bluff Body in the Laminar Vortex Shedding Regime [PDF]
, 2019 Ritvik Dobriyal +3 more
openalex +1 more source
ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling
Advanced Science, EarlyView.ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao +19 more
wiley +1 more source
Investigating the effect of rotational degree of freedom on a circular cylinder at low reynolds number in cross flow [PDF]
, 2011 Numerical simulations of Vortex-Induced Vibrations (VIV) of a circular cylinder in cross flow with a rotational degree of freedom about its axis have been carried out by means of a finite-volume method.
Bahai, H, Madani, SH, Wissink, J
core +1 more source
Passive Control of the Vortex Shedding past a Square Cylinder with Moving Ground Part II Study of Passive Control Technique [PDF]
, 2005 Tae Yoon Kim
openalex +1 more source