Results 251 to 260 of about 2,150,811 (296)

Integrative Multi‐Omics Analysis Reveals a Mitochondrial–Immune Axis Associated With Neoadjuvant Chemotherapy Response in High‐Grade Serous Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang   +11 more
wiley   +1 more source

The Volebny Kompas Datasets on Slovak Voter and Party Positions. [PDF]

open access: yesSci Data
Mintal JM   +6 more
europepmc   +1 more source

TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes

open access: yesAdvanced Science, EarlyView.
In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang   +11 more
wiley   +1 more source

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu   +13 more
wiley   +1 more source

The Responsive Voter: Short-term Influences on Voting Behaviour

1987
Voting is a political act. A simple point but one that can easily disappear in the welter of analyses linking electoral choice to social causes. Further, the influence of purely political factors such as party leaders and political debate is increasing as traditional class and party loyalties weaken and more votes come up for grabs.
Martin Harrop, William L. Miller
openaire   +1 more source

The Impact of Voter Education on Voter Confidence: Evidence from the 2020 U.S. Presidential Election

Election Law Journal: Rules, Politics, and Policy, 2023
Mara Suttmann-Lea, Thessalia Merivaki
exaly  

Who Do Voter ID Laws Keep from Voting?

Journal of Politics, 2022

exaly  

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