Results 91 to 100 of about 48,395 (233)

Clinical and Imaging Characteristics of Parkinson's Disease with Negative Alpha‐Synuclein Seed Amplification Assay

Movement Disorders, EarlyView.
Abstract Background The cerebrospinal fluid alpha‐synuclein seed amplification assay (CSFasynSAA) detects alpha‐synuclein aggregation in over 90% of individuals with sporadic PD (sPD). However, the clinical characteristics of sPD with negative CSFasynSAA remain undefined.
Sarah M. Brooker, Jacopo Pasquini, Seung Ho Choi, David‐Erick Lafontant, Seyed‐Mohammad Fereshtehnejad, Yashar Zeighami, Piergiorgio Grillo, Giulietta M. Riboldi, Houman Azizi, Roqaie Moqadam, Un Jung Kang, Kelly N.H. Nudelman, Andrew Siderowf, Caroline M. Tanner, Thomas F. Tropea, Tatiana Foroud, Lana M. Chahine, Brit Mollenhauer, Kalpana M. Merchant, Douglas Galasko, Christopher S. Coffey, Roseanne D. Dobkin, Ethan G. Brown, Roy N. Alcalay, Daniel Weintraub, Kenneth Marek, Tanya Simuni, Paulina Gonzalez‐Latapi, Nicola Pavese, Kathleen L. Poston, the Parkinson's Progression Markers Initiative   +30 more
wiley   +1 more source

Neural substrates of self‐ and external‐preoccupation: A voxel‐based morphometry study

Brain and Behavior, 2019
Introduction Self‐ and external‐preoccupation have been linked to psychopathological states. The neural substrates underlying self‐ and external‐preoccupation remain unclear. In the present study, we aim to provide insight into the information‐processing
Shigeyuki Ikeda, Hikaru Takeuchi, Yasuyuki Taki, Rui Nouchi, Ryoichi Yokoyama, Seishu Nakagawa, Atsushi Sekiguchi, Kunio Iizuka, Sugiko Hanawa, Tsuyoshi Araki, Carlos Makoto Miyauchi, Kohei Sakaki, Takayuki Nozawa, Susumu Yokota, Daniele Magistro, Ryuta Kawashima   +15 more
doaj   +1 more source

Higher Adolescent Body Mass Index is Associated with Lower Regional Gray and White Matter Volumes and Lower Levels of Positive Emotionality

Frontiers in Neuroscience, 2016
Adolescent obesity is associated with an increased chance of developing serious health risks later in life. Identifying the neurobiological and personality factors related to increases in adiposity is important to understanding what drives maladaptive ...
James T Kennedy, Paul F Collins, Paul F Collins, Monica Luciana, Monica Luciana   +4 more
doaj   +1 more source

Voxel‐Based Morphometry and Voxel‐Based Relaxometry in Parkinsonian Variant of Multiple System Atrophy

Journal of Neuroimaging, 2010
ABSTRACTBACKGROUND AND PURPOSE Multiple system atrophy (MSA) is a progressive neurodegenerative disorder divided into a parkinsonian (MSA‐P) and a cerebellar variant. The purpose of this study was to assess regional brain atrophy and iron content using Voxel‐based morphometry (VBM) and Voxel‐based relaxometry (VBR) respectively, in MSA‐P. METHODS Using
Tzarouchi, L. C., Astrakas, L. G., Konitsiotis, S. T., Tsouli, S., Margariti, P. N., Zikou, A. K., Argyropoulou, M. I.   +6 more
openaire   +4 more sources

Gray Matter Volume Loss in Parkinson's Disease Psychosis and Cannabinoid Receptor Gene Expression in the Brain

Movement Disorders, EarlyView.
Abstract Background Serotonergic and dopaminergic pathways are implicated in Parkinson's disease psychosis (PDP), but preliminary evidence also implicates the endocannabinoid system (ECS). Objectives We examined the association of gray matter volume loss in PDP patients with brain expression of the genes coding for CB1 (cannabinoid type 1) and CB2 ...
Sara Pisani, František Váša, Latha Velayudhan, Sagnik Bhattacharyya   +3 more
wiley   +1 more source

Structural Cerebral Changes and Conduct Disorder

Pediatric Neurology Briefs, 2009
Voxel-based morphometry was used to analyze structural MRI scans from 23 boys with callous-unemotional conduct problems (mean age 11 yrs 8 months) and 25 healthy controls, in a study at the Institute of Psychiatry, King’s College, London, UK, and other ...
J Gordon Millichap
doaj   +1 more source

Interleukin-6 gene (IL-6): a possible role in brain morphology in the healthy adult brain [PDF]

, 2012
Background: Cytokines such as interleukin 6 (IL-6) have been implicated in dual functions in neuropsychiatric disorders. Little is known about the genetic predisposition to neurodegenerative and neuroproliferative properties of cytokine genes.
A Kitamura, AA Willette, AH Miller, AL Jefferson, AL Marsland, AL Sousa, American Psychiatric Association, Astrid V Rauch, AT Beck, B Balasubramaniam, B Viviani, Bernhard T Baune, BL Pierce, BT Baune, BT Baune, Carsten Konrad, CF Terry, Christina Uhlmann, CS Carlson, Dominik Grotegerd, E Brietzke, E Halperin, E Vermetten, Eva Birosova, F Faul, GM MacQueen, H Tilg, H-U Wittchen, Harald Kugel, I HapMap, I Hickie, I Morales, J Ashburner, J Hannestad, J McAfoose, J Oh, JA Wagner, JE Malberg, JM Gatt, JM Kim, Jochen Bauer, JP Godbout, K Kasai, K Pham, Katharina Domschke, KK Bowen, L Capuron, L Christiansen, L Vallieres, L Vitkovic, LD Ward, M Bonafe, M Murphy, M Pickering, M Yamada, MA Kahn, MA Munoz-Fernandez, MK Kang, ML Monje, MT Heneka, N Ohbayashi, N Pervaiz, N Raz, N Tzourio-Mazoyer, O Davidovich, O Islam, P Angelopoulos, P Oeth, P Videbech, Patricia Ohrmann, RA Gadient, RA Gadient, RM Thomas, S Campbell, S Eickhoff, S Ihara, S Ihara, S Lehrl, S Matsuda, S Toulmond, SA Loddick, SD Forman, Sonja Schöning, T Beblo, T Frodl, T Hama, T Hama, T Hirano, Thomas Suslow, U Dannlowski, Udo Dannlowski, V Tancredi, Volker Arolt, Walter Heindel, Y Akaneya, Y Dowlati, Y Kushima, Y Kushima, YP Peng, YY Wu   +99 more
core   +3 more sources

Multi-site voxel-based morphometry — Not quite there yet

NeuroImage, 2011
Voxel-based morphometry (VBM) is a widely applied method in computational neurosciences but it is currently recommended to compare only data collected at a single MRI scanner. Multi-site VBM would be a desirable approach to increase group size and, thus, statistical power. We aimed to assess if multi-site VBM is feasible on similar hardware and compare
Focke, Niels K., Helms, G., Kaspar, S., Diederich, Christine, Toth, V., Dechent, Peter, Mohr, A., Paulus, Walter J.   +7 more
openaire   +3 more sources

Modeling of Fiber Orientation‐Dependent R1 Relaxation in Human White Matter In Vivo Within The Framework of The Transient Hydrogen Bond Model

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Axon fiber orientation‐dependent R1 relaxation in human white matter (WM) in vivo at B0 = 1.5 T, 3 T, and 7 T was studied within the framework of the transient hydrogen bond (THB) model, which attributes MR signal relaxation to quantum magnetization interactions of water and motion‐restricted protons in hydrophilic heads of lipid ...
Dmitriy A. Yablonskiy, Risto A. Kauppinen, Ekaterina Paasonen, Jeromy Thotland, Mervi Könönen, Pramod Pisharady, Christophe Lenglet, Juhana M. Hakumäki, Olli H. J. Gröhn, Michael Garwood, Alexander L. Sukstanskii   +10 more
wiley   +1 more source

Are Cochlear Implants Indicated in the Advanced Aging Population?

The Laryngoscope, EarlyView.
India Jackson, Tiffany Peng Hwa, Michael Ruckenstein   +2 more
wiley   +1 more source