Results 91 to 100 of about 2,832 (180)

Vaccine Potential of Ebola Virus VP24, VP30, VP35, and VP40 Proteins

open access: yesVirology, 2001
Previous vaccine efforts with Ebola virus Zaire (EBOV-Z) emphasized the potential protective efficacies of immune responses to the surface glycoprotein and the nucleoprotein. To determine whether the VP24, VP30, VP35, and VP40 proteins are also capable of eliciting protective immune responses, these genes were expressed from alphavirus replicons and ...
Wilson, Julie A.   +3 more
openaire   +2 more sources

Monoclonal Antibodies and Recombinant Proteins for Immune-Diagnostics of Ebola Virus Disease

open access: yesПроблемы особо опасных инфекций, 2015
The review summarizes the literature data on the studies of viral antigens and antibodies, specific to Ebola virus, suitable for the development of a test-system for immune-diagnostics of the disease caused by them.
E. I. Kazachinskaya   +2 more
doaj   +1 more source

Ebolavirus replication and Tetherin/BST-2

open access: yesFrontiers in Microbiology, 2012
Ebolavirus (EBOV) is an enveloped, non-segmented, negative-stranded RNA virus, which consists of five species: Zaire ebolavirus (ZEBOV), Sudan ebolavirus (SEBOV), Tai Forest ebolavirus (TFEBOV), Bundibugyo ebolavirus (BEBOV), and Reston ebolavirus (REBOV)
Jiro eYasuda
doaj   +1 more source

A Novel Ebola Virus VP40 Matrix Protein-Based Screening for Identification of Novel Candidate Medical Countermeasures

open access: yesViruses, 2020
Filoviruses, such as Ebola virus and Marburg virus, are of significant human health concern. From 2013 to 2016, Ebola virus caused 11,323 fatalities in Western Africa.
Ryan P. Bennett   +10 more
doaj   +1 more source

Full-length Ebola glycoprotein accumulates in the endoplasmic reticulum

open access: yesVirology Journal, 2011
The Filoviridae family comprises of Ebola and Marburg viruses, which are known to cause lethal hemorrhagic fever. However, there is no effective anti-viral therapy or licensed vaccines currently available for these human pathogens.
Bhattacharyya Suchita, Hope Thomas J
doaj   +1 more source

Membrane association and localization dynamics of the Ebola virus matrix protein VP40

open access: yesBiochimica et Biophysica Acta (BBA) - Biomembranes, 2017
The Ebola virus matrix protein VP40 is a major structural protein that provides the scaffolding for new Ebola virus particles. For this, VP40 is first trafficked to the lower leaflet of the plasma membrane (PM) in its dimeric form. Once associated with the PM, the VP40 dimers undergo structural rearrangements and oligomerize into hexamers and filaments
Jeevan B, Gc   +2 more
openaire   +2 more sources

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