Results 161 to 170 of about 2,832 (180)

High Seroreactivities to Orthoebolaviruses in Rural Cameroon: A Case-Control Study on Nonhuman Primate Bites and a Cross-sectional Survey in Rural Populations. [PDF]

J Infect Dis
Ramassamy JL, Ayouba A, Thaurignac G, Bilounga Ndongo C, Nnuka P, Betsem E, Njouom R, Mpoudi Ngole E, Vanhomwegen J, Hoinard D, England P, Journeaux A, Picard C, Thomas D, Pannetier D, Baize S, Delaporte E, Peeters M, Gessain A.   +18 more
europepmc   +1 more source

Molecular insights into nucleocapsid assembly and transport in Marburg and Ebola viruses. [PDF]

mBio
Takamatsu Y, Dolnik O, Hirabayashi A, Okamoto K, Kurashige T, Shangfan H, Oda Harumi C, Noda T.   +7 more
europepmc   +1 more source

Minor electrostatic changes robustly increase VP40 membrane binding, assembly, and budding of Ebola virus matrix protein derived virus-like particles. [PDF]

J Biol Chem
Motsa BB, Sharma T, Cioffi MD, Chapagain PP, Stahelin RV.   +4 more
europepmc   +1 more source

Genomic Evolution and Phylodynamics of the Species Orthomarburgvirus marburgense (Marburg and Ravn Viruses) to Understand Viral Adaptation and Marburg Virus Disease's Transmission Dynamics. [PDF]

Pathogens
Muvunyi CM, Mohamed NS, Siddig EE, Ahmed A.   +3 more
europepmc   +1 more source

Immunogenicity, Pathogenesis, and Host's Immuno-Responses to Marburg Virus Infection. [PDF]

Pathogens
Siddig EE, Ndembi N, Ahmed A, Muvunyi CM.   +3 more
europepmc   +1 more source

Reactive oxygen species-related oxidative changes are associated with splenic lymphocyte depletion in Ebola virus infection. [PDF]

Npj Imaging
Mani V, Chu WT, Yang HJ, Morris CP, Laux J, Byrum R, Cooper K, Liu DX, Wang H, Johnson C, Hadley K, Bernbaum JG, Hart R, Anthony SM, Marketon AE, Bernbaum-Cutler R, Pahar B, Worwa G, Kuhn JH, Crozier I, Calcagno C, Gale E.   +21 more
europepmc   +1 more source

Longitudinal proteome-wide antibody profiling in Marburg virus survivors identifies wing domain immunogen for vaccine design. [PDF]

Nat Commun
Khurana S, Grubbs G, Ravichandran S, Cluff E, Kim J, Kuehne AI, Zak S, Dye JM, Lutwama JJ, Herbert AS.   +9 more
europepmc   +1 more source

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Ebolavirus VP40 redux. Or rather, redox.

Structure, 2023
The virion protein 40 (VP40) forms the viral matrix, mediates budding, and downregulates viral RNA synthesis in ebolaviruses. In this issue of Structure, Werner et al. present a structure of VP40 from Sudan ebolavirus with a previously unresolved disulfide bridge that enables regulation of VP40 functions via human thioredoxin.
openaire   +2 more sources

Identification of novel chemical compounds targeting filovirus VP40-mediated particle production

Antiviral Research, 2022
The central role of Ebola virus (EBOV) VP40 in nascent virion assembly and budding from infected host cells makes it an important therapeutic target. The mechanism of dimerization, following oligomerization of VP40 leading to the production of virus-like particles (VLP) has never been investigated for the development of therapeutic candidates against ...
Shuzo Urata, Olaposi Idowu Omotuyi, Ayako Izumisawa, Takeshi Ishikawa, Satoshi Mizuta, Yasuteru Sakurai, Tatsuaki Mizutani, Hiroshi Ueda, Yoshimasa Tanaka, Jiro Yasuda   +9 more
openaire   +2 more sources

Rapid detection of EBOLA VP40 in microchip immunofiltration assay

SPIE Proceedings, 2015
In the spring of 2014, the Ebola virus (EBOV) strain Zaire caused a dramatic outbreak in several regions of West Africa. The RT-PCR and antigen capture diagnostic proved to be effective for detecting EBOV in blood and serum. In this paper, we present data of a rapid antigen capture test for the detection of VP40.
Peter Miethe, Dominik Gary, Nadine Hlawatsch, Anne-Marie Gad   +3 more
openaire   +1 more source