Vp40 - Open Access .click

Structure, 2023
The virion protein 40 (VP40) forms the viral matrix, mediates budding, and downregulates viral RNA synthesis in ebolaviruses. In this issue of Structure, Werner et al. present a structure of VP40 from Sudan ebolavirus with a previously unresolved disulfide bridge that enables regulation of VP40 functions via human thioredoxin.
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Characterization of the Unconventional Secretion of the Ebola Matrix Protein VP40

2016
While most secreted proteins use the classical endoplasmic reticulum (ER)-Golgi secretion pathway to reach the extracellular medium, a few proteins are secreted through unconventional secretary pathways. Viral proteins can be secreted through unconventional secretion pathways.
Reynard, Olivier, Mateo, Mathieu
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Expression of the VP40 antigen from the Zaire ebolavirus in tobacco plants [PDF]

Planta, 2017
The plant cell is able to produce the VP40 antigen from the Zaire ebolavirus , retaining the antigenicity and the ability to induce immune responses in BALB/c mice. The recent Ebola outbreak evidenced the need for having vaccines approved for human use. Herein we report the expression of the VP40 antigen from the Ebola virus as an initial effort in the
Sergio Rosales-Mendoza +5 more
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Rapid detection of EBOLA VP40 in microchip immunofiltration assay

SPIE Proceedings, 2015
In the spring of 2014, the Ebola virus (EBOV) strain Zaire caused a dramatic outbreak in several regions of West Africa. The RT-PCR and antigen capture diagnostic proved to be effective for detecting EBOV in blood and serum. In this paper, we present data of a rapid antigen capture test for the detection of VP40.
Peter Miethe +3 more
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virus
biology
virology

cell biology
viral matrix protein
ebolavirus

biochemistry
gene
chemistry