Results 81 to 90 of about 8,749 (163)

Establishment and characterization of a Gobiocypris rarus cell line for studying type II grass carp reovirus infection

Aquaculture Reports
The type II Grass Carp Reovirus (GCRV-II) causes severe hemorrhagic disease with high mortality in economically important fish species. However, existing cell culture systems exhibits neither efficient viral replication nor observable cytopathic effects.
Wenji Huang, Sijia Wan, Ling Shao
doaj   +1 more source

Mesenchymal stromal cells secretory pattern contributes to oncoinflammatory bone marrow microenvironment in polycythemia vera

Hematology, Transfusion and Cell Therapy
Introduction: Polycythemia vera is a myeloproliferative neoplasm marked by an increased proliferation of erythroid mature and precursors cells in bone marrow and peripheral blood. The pathophysiology is linked to the presence of the JAK2 driver mutation,
Juçara Gastaldi Cominal, Maira da Costa Cacemiro, Giovana Michelassi Berbel, Rifkath Marie Laurance Rahimy, Gisele Vieira Rocha, Dalila Lucíola Zanette, Maria Carolina Oliveira, Lorena Lobo de Figueiredo-Pontes, Kelen Cristina Ribeiro Malmegrim, Fabíola Attié de Castro   +9 more
doaj   +1 more source

Evaluating the effects of common control measures for influenza A (H1N1) outbreak at school in China: A modeling study.

PLoS ONE, 2017
BackgroundInfluenza A (H1N1) outbreaks have become common at schools in China since 2009. However, the effects of common countermeasures for school influenza outbreak have not been quantified so far, including isolation, vaccination, antivirus and school
Tianmu Chen, Yuanxiu Huang, Ruchun Liu, Zhi Xie, Shuilian Chen, Guoqing Hu   +5 more
doaj   +1 more source

Infectious pancreatic necrosis virus induces apoptosis in vitro and in vivo independent of VP5 expression

Virology, 2005
Infectious pancreatic necrosis virus (IPNV), the causative agent of a highly infectious disease in salmonid fish, encodes a small non-structural protein designated VP5. This protein contains Bcl-2 homologous domains and inhibits apoptosis when expressed in cell culture. We have previously reported the generation of three VP5 mutants of IPNV-Sp serotype,
Santi, Nina, Sandtrø, Ane, Sindre, Hilde, Song, Haichen, Hong, Jiann-Ruey, Thu, Beate, Wu, Jen-Leih, Vakharia, Vikram N., Evensen, Øystein   +8 more
openaire   +2 more sources

The VP53 protein encoded by RNA2 of a fabavirus, broad bean wilt virus 2, is essential for viral systemic infection

Communications Biology
Plant viruses evolves diverse strategies to overcome the limitations of their genomic capacity and express multiple proteins, despite the constraints imposed by the host translation system.
Myung-Hwi Kim, Boram Choi, Seok-Yeong Jang, Ji-Soo Choi, Sora Kim, Yubin Lee, Suejin Park, Sun-Jung Kwon, Jin-Ho Kang, Jang-Kyun Seo   +9 more
doaj   +1 more source

IPNV with high and low virulence: host immune responses and viral mutations during infection

Virology Journal, 2011
Background Infectious pancreatic necrosis virus (IPNV) is an aquatic member of the Birnaviridae family that causes widespread disease in salmonids. IPNV is represented by multiple strains with markedly different virulence.
Skjesol Astrid, Skjæveland Ingrid, Elnæs Marianne, Timmerhaus Gerrit, Fredriksen Børge N, Jørgensen Sven, Krasnov Aleksei, Jørgensen Jorunn B   +7 more
doaj   +1 more source

Generation of VP5 deficient mutant of infectious bursal disease virus strain HZ2

Chinese Science Bulletin, 2006
Infectious bursal disease virus (IBDV) is a bi-segmented, dsRNA virus of the Birnaviridae family. The nonstructural protein VP5 has been reported to be associated with virus-induced cell apoptosis and pathogenicity, but its role in viral replication has not been unequivocally identified.
Long Li, Yongwei Wei, Yaowei Huang, Lian Yu   +3 more
openaire   +1 more source

Neuron-associated retroelement-derived protein Arc/Arg3.1 assists in the early stages of alphaherpesvirus infection in human neuronal cells.

PLoS ONE
Alphaherpesviruses, including herpes simplex virus type 1 (HSV-1) and pseudorabies virus (PRV), are neurotropic double-stranded DNA viruses. Alphaherpesviruses control the expression of various host factors to ensure efficient infection and propagation ...
Hiroko Kobayashi, Mitsuki Yasukochi, Masayuki Horie, Yasuko Orba, Hirofumi Sawa, Kan Fujino, Satoshi Taharaguchi   +6 more
doaj   +1 more source

Infectious bursal disease virus VP5 triggers host shutoff in a transcription-dependent manner

mBio
ABSTRACT Viruses have evolved intricate mechanisms to evade host antiviral responses and exploit cellular resources by manipulating the expression profile of host genes. During infection, viruses encode proteins with shutoff activity to globally inhibit host protein synthesis, which is an effective ...
Xinxin Niu, J. L. Han, Mengmeng Huang, Guodong Wang, Yulong Zhang, Wenying Zhang, Hannah Yu, Mengyi Xu, Kai Li, Li Gao, Suyan Wang, Yuntong Chen, Hongyu Cui, Yanping Zhang, Changjun Liu, Xiaomei Wang, Yulong Gao, Xiaoping Qi   +17 more
openaire   +3 more sources

Plasmid DNA-based reverse genetics as a platform for manufacturing of bluetongue vaccine

Journal of Virology
Control of bluetongue disease is predominantly through vaccination with licensed inactivated or live-attenuated vaccines (LAVs). Manufacturing of LAVs in endemic countries requires formulation with a high number of serotypes for effective protection ...
Tendai A. M. Mlingo, Jacques Theron, Nobalanda B. Mokoena   +2 more
doaj   +1 more source