Results 61 to 70 of about 10,250 (201)
iScience, 2022 Summary: Non-replicating rotavirus vaccines are an alternative strategy to improve the efficacy and safety of rotavirus vaccines. The spike protein VP4, which could be enzymatically cleaved into VP8∗ and VP5∗, is an ideal target for the development of ...
Guoxing Luo +11 more
doaj +1 more source
BMC Plant BiologyBackground Heat stress (HS) negatively impacts crop yield and quality worldwide. Abscisic acid (ABA) is well known to play critical roles in stress responses.
Yanpei Liu +6 more
doaj +1 more source
N-Terminal Myristoylated VP5 is Required for Penetrating Cell Membrane and Promoting Infectivity in Aquareoviruses [PDF]
Virologica Sinica, 2018 Nonenveloped animal viruses must disrupt the host cell membrane to initiate infection. Although myristoylated outer capsid protein is known to be responsible for membrane penetration in nonenveloped viruses, the mechanisms underlying membrane penetration to enter the host cytoplasm remain poorly understood, compared to the membrane fusion mechanisms of
Qingxiu Chen +3 more
openaire +2 more sources
Maize Biofortification Approaches for Fighting Malnutrition in Sub‐Saharan Africa
Plant-Environment Interactions, Volume 7, Issue 4, August 2026.ABSTRACT Maize is a staple food in sub‐Saharan Africa (SSA); however, commonly used maize varieties are deficient in essential nutrients, including lysine, tryptophan, vitamin A, and minerals such as iron (Fe) and zinc (Zn). As a result, millions of people in this region suffer from one or more nutrient deficiencies that commonly lead to malnutrition ...
Bitew Tilahun Engida +2 more
wiley +1 more source
, 2009 International audienceThe outer-coat proteins, VP2 and VP5, of epizootic haemorrhagic disease virus (EHDV) are important for host cell binding during the initiation of infection. They are also known to determine virus serotype.
Maan, S +9 more
core +1 more source
Small Methods, Volume 10, Issue 16, 25 August 2026.An advanced patterning method is presented for metal‐assisted chemical etching. The interlayer replaces the resist and enables catalyst deposition on a clean interface. The prepared samples show improved performance with a more reproducible etching profile, higher aspect ratio, and increased consistency over a larger area.
Bryan Peter Jost Benz +2 more
wiley +1 more source
PLoS ONE, 2013 The protective efficacy of recombinant vaccines expressing serotype 8 bluetongue virus (BTV-8) capsid proteins was tested in a mouse model. The recombinant vaccines comprised plasmid DNA or Modified Vaccinia Ankara viruses encoding BTV VP2, VP5 or VP7 ...
Tamara Kusay Jabbar +10 more
doaj +1 more source
Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus
Advanced Science, Volume 13, Issue 42, 28 July 2026.This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan +11 more
wiley +1 more source
The rotavirus VP5*/VP8* conformational transition permeabilizes membranes to Ca2+
PLOS PathogensRotaviruses infect cells by delivering into the cytosol a transcriptionally active inner capsid particle (a "double-layer particle": DLP). Delivery is the function of a third, outer layer, which drives uptake from the cell surface into small vesicles from which the DLPs escape.
Marilina de Sautu +4 more
openaire +3 more sources
Journal of Medical Virology, Volume 98, Issue 5, May 2026.ABSTRACT Rotavirus gastroenteritis decreased substantially worldwide during the COVID‐19 pandemic, and activity remained minimal in Hokkaido Prefecture, Japan, for 5 years after 2020. Hospital‐based surveillance in Hokkaido since July 2019 identified the first resurgence of rotavirus gastroenteritis in 2025.
Yuya Fukuda +20 more
wiley +1 more source