Results 51 to 60 of about 9,619 (201)

First Investigation of Grass Carp Reovirus (GCRV) Infection in Amphioxus: Insights into Pathological Effects, Transmission, and Transcriptomic Responses

Viruses
Amphioxus belongs to the subphylum Cephalochordata and occupies a transitional position in evolution between invertebrates and vertebrates. Due to the lack of viruses suitable for immunostimulation in amphioxus, this study for the first time explored the
Jingyuan Lin, Meng Yang, Huijuan Yang, Guangdong Ji, Zhenhui Liu   +4 more
doaj   +1 more source

Bivalent rotavirus VP4∗ stimulates protective antibodies against common genotypes of human rotaviruses

iScience, 2022
Summary: Non-replicating rotavirus vaccines are an alternative strategy to improve the efficacy and safety of rotavirus vaccines. The spike protein VP4, which could be enzymatically cleaved into VP8∗ and VP5∗, is an ideal target for the development of ...
Guoxing Luo, Yuanjun Zeng, Han Yang, Yijian Li, Lianwei Yang, Cao Li, Feibo Song, Shiyin Zhang, Tingdong Li, Shengxiang Ge, Jun Zhang, Ningshao Xia   +11 more
doaj   +1 more source

Membrane Composition Modulates Vp54 Binding: A Combined Experimental and Computational Study

Pathogens
The recruitment of peripheral membrane proteins is tightly regulated by membrane lipid composition and local electrostatic microenvironments. Our experimental observations revealed that Vp54, a viral matrix protein, exhibited preferential binding to ...
Wenhan Guo, Rui Dong, Ayoyinka O. Okedigba, Jason E. Sanchez, Irina V. Agarkova, Elea-Maria Abisamra, Andrew Jelinsky, Wayne Riekhof, Laila Noor, David D. Dunigan, James L. Van Etten, Daniel G. S. Capelluto, Chuan Xiao, Lin Li   +13 more
doaj   +1 more source

New insights into rotavirus entry machinery: stabilization of rotavirus spike conformation is independent of trypsin cleavage. [PDF]

PLoS Pathogens, 2014
The infectivity of rotavirus, the main causative agent of childhood diarrhea, is dependent on activation of the extracellular viral particles by trypsin-like proteases in the host intestinal lumen.
Javier M Rodríguez, Francisco J Chichón, Esther Martín-Forero, Fernando González-Camacho, José L Carrascosa, José R Castón, Daniel Luque   +6 more
doaj   +1 more source

The effect of pH on the structure of Bluetongue virus VP5

Journal of General Virology
The unenveloped Bluetongue virus capsid comprises several structural layers, the inner two comprising a core, which assembles before addition of the outer proteins, VP2 and VP5. Two symmetric trimers of VP5 fit like pegs into two distinct pits on the core and undergo pH conformational changes in the context of the virus, associated with cell entry ...
Hanwen Zhang, Kamel El Omari, Geoff Sutton, David I. Stuart   +3 more
openaire   +3 more sources

Genetic Analysis of Field Isolates of Infectious Bursal Disease Virus in Iraqi Farms

The Iraqi Journal of Veterinary Medicine, 2020
Sixty samples of bursa of Fabricius were collected from broiler chickens suspected to be infected with infectious bursal disease virus (IBDV) in different areas of Iraq for molecular evaluation.
Rawaa S. Jumaa, Aida B. Allawi, Rebah N. Jabbar   +2 more
doaj   +1 more source

Selective Membrane Permeabilization by the Rotavirus VP5* Protein Is Abrogated by Mutations in an Internal Hydrophobic Domain [PDF]

Journal of Virology, 2000
ABSTRACT Rotavirus infectivity is dependent on the proteolytic cleavage of the VP4 spike protein into VP8* and VP5* proteins. Proteolytically activated virus, as well as expressed VP5*, permeabilizes membranes, suggesting that cleavage exposes a membrane-interactive domain of VP5* which effects rapid viral entry. The VP5* protein
W, Dowling, E, Denisova, R, LaMonica, E R, Mackow   +3 more
openaire   +2 more sources

A putative cell surface receptor for white spot syndrome virus is a member of a transporter superfamily. [PDF]

PLoS ONE, 2012
White spot syndrome virus (WSSV), a large enveloped DNA virus, can cause the most serious viral disease in shrimp and has a wide host range among crustaceans.
Huai-Ting Huang, Jiann-Horng Leu, Po-Yu Huang, Li-Li Chen   +3 more
doaj   +1 more source

Duck Orbivirus and Egg Production: A Newly Identified Duck Orbivirus Is the Etiological Agent of Egg Production Decline in Chinese Breeder Ducks

Animal Research and One Health, EarlyView.
Field samples from breeder duck farms with egg‐production decline were subjected to viral detection, genome sequencing, and virus isolation. Experimental infection demonstrated that duck orbivirus (DORV) causes a significant and persistent reduction in egg production in breeder ducks.
Bing Li, Jianhua Wang, Xuezhi Cui, Xinxing Chu, You Wang, Dongmin Hao, Mingqing Xu, Haixia Chang, Huihui Li, Mingtian Mao, Mian Wu, Chengguang Lu, Jing Tang, Suyun Liang, Zhanbao Guo, Zhengkui Zhou, Youxiang Diao, Shuisheng Hou, Yi Tang   +18 more
wiley   +1 more source

Grinding behavior of VP50IM steel using green and black silicon carbide compared to aluminum oxide wheel under different feed rates

, 2021
Technological advances and the development of new products make it increasingly necessary to seek to improve production means to meet the growing demand for equipment and consumer goods.
Sanchez, Luiz Eduardo De Angelo [UNESP], Ribeiro, Fernando Sabino Fonteque, Bianchi, Eduardo Carlos [UNESP], Cuesta, Jorge Luiz [UNESP], Lopes, José Claudio [UNESP], Garcia, Mateus Vinicius [UNESP], de Mello, Hamilton José [UNESP], de Moraes, Douglas Lyra [UNESP], da Silva, Andrigo Elisiario [UNESP], Aguiar, Paulo Roberto [UNESP]   +9 more
core   +1 more source