Accumulating evidence indicates that mammalian NIMA (never in mitosis, gene A)-related kinase 6 (NEK6) plays potential roles during the course of tumorigenesis, but little is known about NEK6 in lower vertebrates. Herein, we reported a mammalian ortholog
Xiaowen Xu +7 more
doaj +1 more source
A full UL13 open reading frame in Marek’s disease virus (MDV) is dispensable for tumor formation and feather follicle tropism and cannot restore horizontal virus transmission of rRB-1B in vivo [PDF]
peer reviewedMarek’s disease virus (MDV) is an oncogenic alphaherpesvirus that is highly contagious in poultry. Recombinant RB-1B (rRB-1B) reconstituted from an infectious genome cloned as a bacterial artificial chromosome (BAC) is unable to spread ...
Beaumont, Catherine +6 more
core +4 more sources
Amphioxus belongs to the subphylum Cephalochordata and occupies a transitional position in evolution between invertebrates and vertebrates. Due to the lack of viruses suitable for immunostimulation in amphioxus, this study for the first time explored the
Jingyuan Lin +4 more
doaj +1 more source
Summary: Non-replicating rotavirus vaccines are an alternative strategy to improve the efficacy and safety of rotavirus vaccines. The spike protein VP4, which could be enzymatically cleaved into VP8∗ and VP5∗, is an ideal target for the development of ...
Guoxing Luo +11 more
doaj +1 more source
Membrane Composition Modulates Vp54 Binding: A Combined Experimental and Computational Study
The recruitment of peripheral membrane proteins is tightly regulated by membrane lipid composition and local electrostatic microenvironments. Our experimental observations revealed that Vp54, a viral matrix protein, exhibited preferential binding to ...
Wenhan Guo +13 more
doaj +1 more source
New insights into rotavirus entry machinery: stabilization of rotavirus spike conformation is independent of trypsin cleavage. [PDF]
The infectivity of rotavirus, the main causative agent of childhood diarrhea, is dependent on activation of the extracellular viral particles by trypsin-like proteases in the host intestinal lumen.
Javier M Rodríguez +6 more
doaj +1 more source
Assembly of Replication-Incompetent African Horse Sickness Virus Particles: Rational Design of Vaccines for All Serotypes. [PDF]
UNLABELLED: African horse sickness virus (AHSV), an orbivirus in the Reoviridae family with nine different serotypes, causes devastating disease in equids.
Aebischer, Andrea +5 more
core +2 more sources
Genetic Analysis of Field Isolates of Infectious Bursal Disease Virus in Iraqi Farms
Sixty samples of bursa of Fabricius were collected from broiler chickens suspected to be infected with infectious bursal disease virus (IBDV) in different areas of Iraq for molecular evaluation.
Rawaa S. Jumaa +2 more
doaj +1 more source
Plasmons of a two-dimensional electron gas in the presence of spin orbit interaction [PDF]
A theoretical study of the collective excitation associated with plasmon modes is presented for a two-dimensional electron gas in the presence of spin orbit (SO) interaction induced by the Rashba effect.
Xu, W.
core +1 more source
A putative cell surface receptor for white spot syndrome virus is a member of a transporter superfamily. [PDF]
White spot syndrome virus (WSSV), a large enveloped DNA virus, can cause the most serious viral disease in shrimp and has a wide host range among crustaceans.
Huai-Ting Huang +3 more
doaj +1 more source

