Viruses, 2021 The bluetongue virus (BTV) is transmitted by Culicoides biting midges and causes bluetongue (BT), an OIE-notifiable disease of ruminants. At least 29 BTV serotypes are described as determined by the outer shell proteins VP2 and VP5.
Piet A. van Rijn +2 more
doaj +1 more source
Genotype II Live-Attenuated ASFV Vaccine Bearing 24 Genes Deletion in 3 Independent Regions Is Able to Provide Complete Protection Against Homologous Lethal Challenge. [PDF]
FASEB JAfrican swine fever (ASF) is a highly contagious and lethal viral disease of swine. Therefore, it is urgent to develop a safe and effective vaccine. We constructed a live‐attenuated ASF vaccine bearing 24 gene deletions in 3 independent regions, ASFV‐Δ24.
Xu F +8 more
europepmc +2 more sources
A 3D model of the membrane protein complex formed by the white spot syndrome virus structural proteins. [PDF]
PLoS ONE, 2010 BACKGROUND: Outbreaks of white spot disease have had a large negative economic impact on cultured shrimp worldwide. However, the pathogenesis of the causative virus, WSSV (whit spot syndrome virus), is not yet well understood.
Yun-Shiang Chang +11 more
doaj +1 more source
The Kinetics of VP5 mRNA Expression Is Not Critical for Viral Replication in Cultured Cells [PDF]
Journal of Virology, 2000 ABSTRACTWe generated recombinant viruses in which the kinetics of expression of the leaky-late VP5 mRNA was altered. We then analyzed the effect of such alterations on viral replication in cultured cells. The VP5 promoter and leader sequences from positions −36 to +20, containing the TATA box and an initiator element, were deleted and replaced with a ...
P T, Lieu, E K, Wagner
openaire +2 more sources
The rotavirus VP5*/VP8* conformational transition permeabilizes membranes to Ca 2+
, 2023 ABSTRACT Rotaviruses infect cells by delivering into the cytosol a transcriptionally active inner capsid particle (a "double-layer particle": DLP). Delivery is the function of a third, outer layer, which drives uptake from the cell surface into small vesicles from which the DLPs escape.
Marilina De Sautu +3 more
openaire +2 more sources
Membrane permeabilization of the African horse sickness virus VP5 protein is mediated by two N-terminal amphipathic α-helices [PDF]
, 2011 The VP5 outer capsid protein of African horse sickness virus (AHSV) is cytotoxic when expressed in Spodoptera frugiperda (Sf-9) cells. Secondary structure analysis of the VP5 amino acid sequence of AHSV-9 identified two N-terminal amphipathic α-helices ...
Huismans, H. (Henk), 1942- +2 more
core +1 more source
Genetic and phylogenetic analysis of the outer capsid protein genes of Indian isolates of bluetongue virus serotype-16 [PDF]
Veterinary World, 2018 Aim: The aim of the study was to characterize bluetongue virus serotype 16 (BTV-16), recently isolated from different states of India. The evolutionary relationship of newly isolated BTV-16 and previously reported Indian and global BTV-16 isolates were ...
Arpit Saxena +9 more
doaj +1 more source
Primed for Discovery: Atomic-Resolution Cryo-EM Structure of a Reovirus Entry Intermediate
Viruses, 2010 A recently solved structure of the aquareovirus virion (Zhang, X; Jin, L.; Fang, Q; Hui, W.H.; Zhou Z.H. 3.3 Å Cryo-EM Structure of a Nonenveloped Virus Reveals a Priming Mechanism for Cell Entry.
Shane D. Trask +2 more
doaj +1 more source
Viruses, 2020 Members of the Reoviridae family assemble virus factories within the cytoplasm of infected cells to replicate and assemble virus particles. Bluetongue virus (BTV) forms virus inclusion bodies (VIBs) that are aggregates of viral RNA, certain viral ...
Bjorn-Patrick Mohl +4 more
doaj +1 more source
The linear plasmid prophage Vp58.5 of Vibrio parahaemolyticus is closely related to the integrating phage VHML and constitutes a new incompatibility group of telomere phages [PDF]
, 2009 Vibrio parahaemolyticus O3:K6 pandemic strains recovered in Chile frequently possess a 42-kb plasmid which is the prophage of a myovirus. We studied the prototype phage VP58.5 and show that it does not integrate into the host cell chromosome but ...
Zabala, Beatriz +7 more
core +1 more source