Results 31 to 40 of about 1,611 (152)
Signal Transduction by VIP and PACAP Receptors
Biomedicines, 2022 Homeostasis of the human immune system is regulated by many cellular components, including two neuropeptides, VIP and PACAP, primary stimuli for three class B G protein-coupled receptors, VPAC1, VPAC2, and PAC1.
Ingrid Langer +4 more
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Vasoactive intestinal peptide and its receptors in human ovarian cortical follicles. [PDF]
PLoS ONE, 2012 BACKGROUND: Ovarian cryopreservation is one option for fertility preservation in patients with cancer. The danger of reseeding malignancies could be eliminated by in vitro maturation of primordial follicles from the frozen-thawed tissue.
Rinat Gabbay-Benziv +8 more
doaj +1 more source
Biology, 2022 Vasoactive Intestinal Peptide (VIP) and Pituitary Adenylate-Cyclase-Activating Peptide (PACAP) are anti-inflammatory neuropeptides that play important roles in human and rodent gut microbiota homeostasis and host immunity.
Emma Hawley +5 more
doaj +1 more source
VPAC Receptor Subtypes Tune Purinergic Neuron-to-Glia Communication in the Murine Submucosal Plexus
Frontiers in Cellular Neuroscience, 2017 The enteric nervous system (ENS) situated within the gastrointestinal tract comprises an intricate network of neurons and glia which together regulate intestinal function. The exact neuro-glial circuitry and the signaling molecules involved are yet to be
Pieter Vanden Berghe +6 more
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Expression of VPAC1 in a murine model of allergic asthma [PDF]
Journal of Occupational Medicine and Toxicology, 2013 Abstract Vasoactive intestinal polypeptide (VIP) is a putative neurotransmitter of the inhibitory non-adrenergic non-cholinergic nervous system and influences the mammalian airway function in various ways. Hence known for bronchodilatory, immunomodulatory and mucus secretion modulating effects by interacting with the VIP receptors VPAC1 and ...
Lauenstein, Hans-Dieter +4 more
openaire +4 more sources
PET Imaging of VPAC1 Expression in Experimental and Spontaneous Prostate Cancer [PDF]
Journal of Nuclear Medicine, 2007 Among U.S. men, prostate cancer (PC) accounts for 29% of all newly diagnosed cancers. A reliable scintigraphic agent to image PC and its metastatic or recurrent lesions and to determine the effectiveness of its treatment will contribute to the management of this disease. All PC overexpresses VPAC1 receptors.
Kaijun, Zhang +9 more
openaire +2 more sources
Abstract 4163: Targetting VPAC1 for intestinal cancer prevention
Cancer Research, 2015 Abstract Vasoactive intestinal peptide (VIP) is a neurotransmitter that primarily functions as a vasodilator. VIP plays its role through binding to its receptors known as VIP/pituitary adenylate cyclase-activating peptide receptors (VPACs).
Shaohua Liu, Yunjie Zeng, Nengtai Ouyang
openaire +3 more sources
Probing the VIPR2 Microduplication Linkage to Schizophrenia in Animal and Cellular Models
Frontiers in Neuroscience, 2021 Pituitary adenylate cyclase-activating polypeptide (PACAP, gene name ADCYAP1) is a multifunctional neuropeptide involved in brain development and synaptic plasticity.
Yukio Ago +6 more
doaj +1 more source
Biology, 2022 The relationship between inflammatory bowel disease and sleep disturbances is complicated and of increasing interest. We investigated the inflammatory and immunological consequences of EA in sleep-deprived colitis and found that dextran sulfate sodium ...
Geng-Hao Liu +11 more
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The PACAP/PAC1 Receptor System and Feeding
Brain Sciences, 2021 Pituitary adenylyl cyclase activating polypeptide (PACAP) belongs to the vasoactive intestinal polypeptide (VIP)/secretin/glucagon superfamily. PACAP is present in two forms (PACAP-38 and PACAP-27) and binds to three guanine-regulatory (G) protein ...
Keerthana Sureshkumar +3 more
doaj +1 more source