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Structure-Function Relationship of Vpr: Biological Implications
Current HIV Research, 2009Vpr, incorporated into the HIV-1 virion, shows multiple activities including nuclear transport of the preintegration complex to the nucleus, activation of the transcription, cell cycle arrest at the G2/M transition and induction of apoptosis. Vpr controls many host cell functions through a variety of biological activities and by interaction with ...
Morellet, Nelly +2 more
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SE-VPR: Semantic Enhanced VPR Approach for Visual Localization
2022 Asia Conference on Algorithms, Computing and Machine Learning (CACML), 2022Haoyuan Pei, Jikai Wang, Zonghai Chen
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Biochemical and Biophysical Research Communications, 1999
Vpr, an accessory gene product of HIV-1 which induces cell cycle abnormality leading to the increased HIV replication, is supposed to be a possible target for anti-AIDS drugs. We recently established a cell line (MIT-23) in which Vpr-induced cell cycle perturbation could be manipulated by a tetracycline promoter.
M, Shimura +6 more
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Vpr, an accessory gene product of HIV-1 which induces cell cycle abnormality leading to the increased HIV replication, is supposed to be a possible target for anti-AIDS drugs. We recently established a cell line (MIT-23) in which Vpr-induced cell cycle perturbation could be manipulated by a tetracycline promoter.
M, Shimura +6 more
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VPR model explores the structure of reality through layered levels of organization, introducing the idea of informational energy as a key factor in understanding the behavior of both massless and massive forms.Key elements of the model include:A multi-level structure of reality, where each level is defined by increasing complexity and self-organization.
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Cytocidal activities of hiv-1 vpr are shared by primate lentivirus vpr and vpx relatives
Protein & Peptide Letters, 1998Abstract: The ability of HIV-1 Vpr to kill human cells has been shown to be due to the sequence, HFRIGCRHSRIG, comprising Vpr amino acid residues 71-82. In this study cell killing by Vpr equivalents in other primate lentiviruses has been examined. Five purified synthetic peptides, related to the bioactive region ofHIV-1 Vpr and derived from HIV-2 Vpr ...
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VPR+ Supplement: Resonant Phenomena Across Scales
This supplement extends the VPR (Vortex–Pattern–Resonance) model by introducing VPR+, a framework applying the concept of informational energy to resonant stabilization across multiple organizational levels. The work focuses on two domains: protein stability optimization (e.g., insulin) and temporal structuring of fast radio bursts (FRBs).openaire +1 more source
ConvG-Sem VPR: ConvG Aggregate and Semantic Search VPR Approach for Visual Localization
Pengyu Yi +3 moreopenaire +1 more source