Results 41 to 50 of about 3,834 (193)

Molecular characterization of vancomycin-resistant Staphylococcus aureus strains isolated from clinical samples: A three year study in Tehran, Iran.

open access: yesPLoS ONE, 2017
IntroductionEmergence of vancomycin-intermediate Staphylococcus aureus (VISA) and vancomycin-resistant S. aureus (VRSA) strains has led to great concern in global public health in both developing and developed countries.
Marjan Shekarabi   +4 more
doaj   +1 more source

PREVALENCE OF MRSA AND VRSA IN KALABURAGI REGION

open access: yesInternational Journal of Pharmacy and Biological Sciences, 2016
*Corresponding Author Email: smgaddad@gmail.com ABSTRACT Objective: Prevalence of drug resistance in Staphylococcal infections is steadily increasing in global health care systems. The present study was conducted to determine the prevalence of MRSA and VRSA in Kalaburagi region.
Suresh Kumar Mendem   +3 more
openaire   +1 more source

Chemical Synthesis of Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii Capsular Polysaccharide Fragments as Leads for Cross‐Protection

open access: yesAngewandte Chemie, Volume 138, Issue 6, 2 February 2026.
A total of 16 chemically synthesized capsular polysaccharide (CPS) fragments related to Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii were analyzed by glycan microarray. Comparative screening revealed three conserved epitopes that act as cross‐protective vaccine lead candidates against multidrug‐resistant (MDR) bacterial ...
Amar Kumar Mishra   +9 more
wiley   +2 more sources

Tackling strong biofilm and multi-virulent vancomycin-resistant Staphylococcus aureus via natural alkaloid-based porous nanoparticles: perspective towards near future eradication

open access: yesFrontiers in Cellular and Infection Microbiology
IntroductionAs a growing direction, nano-based therapy has become a successful paradigm used to address the phytogenic delivery-related problems in overcoming multivirulent vancomycin-resistant Staphylococcus aureus (VRSA) infection.MethodsHence, our aim
Marwa I. Abd El-Hamid   +12 more
doaj   +1 more source

The prevalence of vancomycin-resistant Staphylococcus aureus in Ethiopia: a systematic review and meta-analysis

open access: yesAntimicrobial Resistance and Infection Control, 2023
Introduction Vancomycin-resistant Staphylococcus aureus, identified as a “high priority antibiotic-resistant pathogen” by the World Health Organization, poses a significant threat to human health.
Melaku Ashagrie Belete   +7 more
doaj   +1 more source

Effects of VRSA infection on cytotoxicity.

open access: yes, 2013
Cytotoxicity toward control scramble (5S-5) or G6PD-deficient (5.20) cells that were inoculated with the VRSA strain SJC1200 (MOI=100) in the presence/absence of vancomycin (32 μg/ml) for 16 h.
Hung-Yao Ho (479549)   +5 more
core   +1 more source

Beyond Nature's Blueprint: Macrocyclic Peptides Containing Unnatural Amino Acids in Therapeutic Development

open access: yesAngewandte Chemie International Edition, EarlyView.
Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma   +5 more
wiley   +1 more source

Improved Incorporation of Arylglycines Into Ramoplanin Sequences via Solid‐Phase Peptide Synthesis

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 30, 12 August 2026.
The incorporation of arylglycines using solid‐phase peptide synthesis remains challenging due to the sensitivity of these residues for epimerization. Here, exploring multiple conditions for the incorporation of arylglycine residues into peptides using SPPS demonstrates how small changes to current synthesis protocols can lead to significant ...
Edward Marschall   +3 more
wiley   +1 more source

Applications of Bioinorganic Nano‐Based Delivery Systems—Diagnostics and Therapeutics

open access: yesDrug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT Nanotechnology has emerged as a promising avenue for producing nanomedicines as alternatives to conventional drugs. Many organic nanoparticles, such as liposomes used in formulations like Doxil, Onivyde, and Marqibo, are approved by the Food and Drug Administration (FDA) and instrumental in treating various types of cancers.
Frank Ssengooba   +2 more
wiley   +1 more source

Vancomycin-resistant Staphylococcus aureus isolated from camel meat and slaughterhouse workers in Egypt

open access: yesAntimicrobial Resistance and Infection Control, 2019
Background The emergence of vancomycin-resistant Staphylococcus aureus (VRSA) represents a challenge for the treatment of staphylococcal infections in both human and animals worldwide.
Khaled Al-Amery   +7 more
doaj   +1 more source

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