Results 71 to 80 of about 1,849,598 (165)

Virus‐Assembled Biofunctional Microarrays with Hierarchical 3D Nano‐Reticular Network

Advanced Functional Materials, Volume 35, Issue 14, April 3, 2025.
Virus‐assembled microdots with a wrinkled pattern induced by the high‐pressure carbon dioxide method show a morphology similar to sunflowers. Abstract Three‐dimensional (3D) hierarchical wrinkled materials built with biological entities have so far remained exclusive to nature.
Lei Tian, Shadman Khan, Amid Shakeri, Kyle Jackson, Ahmed T. Saif, Fereshteh Bayat, Leon He, Jimmy Gu, Yingfu Li, Tohid F. Didar, Zeinab Hosseinidoust   +10 more
wiley   +1 more source

Classification of the nucleolytic ribozymes based upon catalytic mechanism [PDF]

, 2019
The nucleolytic ribozymes carry out site-specific RNA cleavage reactions by nucleophilic attack of the 2’-oxygen atom on the adjacent phosphorus with an acceleration of a million-fold or greater.
A Ferré-D'Amaré, A Forster, A Hampel, A Hampel, A Ke, A McLeod, A Perrotta, A Perrotta, A Ren, A Ren, A Roth, B Saville, B Saville, C Gaines, C Gaines, C Gaines, C Hutchins, D Eiler, D Klein, D Klein, F Jones, F Westheimer, G Slim, G Soukup, H van Tol, J Buzayan, J Cochrane, J Han, J Haseloff, J Murray, J Thomas, K Harris, K Young, L Hegg, L Kapinos, L Nguyen, L Zheng, M Canny, M Kuo, M Martick, M Oivanen, N Suslov, P Bevilacqua, P Rupert, R Breaker, S Das, S Kath-Schorr, S Koo, S Li, S Nakano, T Lee, T Wilson, T Wilson, T Wilson, T Wilson, W Winkler, Y Komatsu, Y Li, Y Liu, Y Liu, Z Weinberg, Z Weinberg   +61 more
core   +3 more sources

The Critical Role of Inhibitor of Differentiation 4 in Breast Cancer: From Mammary Gland Development to Tumor Progression

Cancer Medicine, Volume 14, Issue 7, April 2025.
ABSTRACT Inhibitor of differentiation 4 (ID4) is a highly conserved DNA‐binding inhibitory protein of mammals, and its main role is to bind basic helix–loop–helix (b‐HLH) so that it loses its DNA‐binding activity, which in turn regulates the transcription of key genes, regulating cell differentiation and proliferation as the physiological function ...
Yuhang Song, Panshi Zhang, Sudhanshu Bhushan, Xinhong Wu, Hongmei Zheng, Yalong Yang   +5 more
wiley   +1 more source

Robust self-replication of combinatorial information via crystal growth and scission [PDF]

, 2012
Understanding how a simple chemical system can accurately replicate combinatorial information, such as a sequence, is an important question for both the study of life in the universe and for the development of evolutionary molecular design techniques ...
B. Yurke, Bullard, Cairns-Smith, Carnall, Collins, Deck, Dutta, E. Winfree, Huppa, Johnston, Knowles, Mao, Orgel, Paul, R. Schulman, Rasmussen, Rothemund, Rothemund, Rubinov, Schrum, Seeman, Smalley, Smith, Viedma, Wang, Wang, Winfree, Wochner   +27 more
core   +3 more sources

Structural Biology of RNA and Protein‐RNA Complexes after AlphaFold3

ChemBioChem, Volume 26, Issue 7, April 1, 2025.
AlphaFold is a great research accelerator and hypothesis generator for structural biology and beyond. With the release of AlphaFold3, RNA and protein‐RNA complex structure prediction is readily possible. This review assesses the reliability of these predictions.
Janosch Hennig
wiley   +1 more source

Properties and Cultivation of Fusarium spp. to Produce Mycoprotein as an Alternative Protein Source

Sustainable Food Proteins, Volume 3, Issue 1, March 2025.
This review explores the potential of Fusarium species in producing mycoprotein, a sustainable alternative protein source. It also delves into the origin of Fusarium species and its history related to mycoprotein production, nutrient assimilation, cultivation methods, nutritional and rheological properties, market presence, sustainability, and legal ...
Ramona Cheriaparambil, Lutz Grossmann
wiley   +1 more source

Method of identifying inhibitors of glutathione S-transferase (GST) gene expression [PDF]

, 1999
Complementary DNA and genomic clones for three variants of GST-.pi. are disclosed. It is demonstrated that certain of these variants are overexpressed in gliomas, thereby indicating an involvement with that form of cancer.
Akande, Olanike, Ali-Osman, Francis, Antoun, Gamil, Buolamwini, John K., Keller, Charles W., Lo, Hui-Wen, Lopez-Berestein, Gabriel   +6 more
core   +1 more source

Comparison of the Structures and Mechanisms of the Pistol and Hammerhead Ribozymes [PDF]

, 2019
Comparison of the secondary and three-dimensional structures of the hammerhead and pistol ribozymes reveals many close similarities, so in this work we have asked if they are mechanistically identical.
Dai, Qing, Li, Nan-Sheng, Lilley, David M. J., Liu, Yijin, Piccirilli, Joseph A., Wilson, Timothy J.   +5 more
core   +3 more sources

Aptamers in oncology: a diagnostic perspective [PDF]

, 2008
Nucleic acid sequences can produce a wide variety of three-dimensional conformations. Some of these structural forms are able to interact with proteins and small molecules with high affinity and specificity.
Khan, Huma, Missailidis, Sotiris
core  

Primordial RNA Replication and Applications in PCR Technology [PDF]

, 2013
The emergence of self-replication and information transmission in life's origin remains unexplained despite extensive research on the topic. A hypothesis explaining the transition from a simple organic world to a complex RNA world is offered here based ...
Palasek, Stan
core