Results 1 to 10 of about 46,208 (194)

Comparative Study of Different Methods in Vibration-Based Terrain Classification for Wheeled Robots with Shock Absorbers [PDF]

Sensors, 2019
Autonomous robots that operate in the field can enhance their security and efficiency by accurate terrain classification, which can be realized by means of robot-terrain interaction-generated vibration signals.
Mingliang Mei, Ji Chang, Yuling Li, Zerui Li, Xiaochuan Li, Wenjun Lv   +5 more
doaj   +3 more sources

Comparison of radiological and pathological tools to assess response to neoadjuvant treatment in resected pancreatic ductal adenocarcinoma patients [PDF]

Therapeutic Advances in Medical Oncology
Background: In non-metastatic pancreatic adenocarcinoma (PDAC), the appropriate evaluation of tumor response to neoadjuvant treatment (NAT) has a substantial prognostic impact, but the tools used to assess it are imperfect and sometimes discordant ...
Anaïs Jenvrin, Riccardo Sartoris, Safi Dokmak, Anne-Laure Védie, Lucie Laurent, Matthieu Tihy, Alain Sauvanet, Vinciane Rebours, Maxime Ronot, Claire Bongrain, Anne Couvelard, Jérôme Cros, Louis de Mestier   +12 more
doaj   +2 more sources

Polyphosphate Polymerase—A Key Enzyme for the Phosphorus Economy of the Microalgal Cell and the Sustainable Usage of This Nutrient [PDF]

Plants
Phosphorus is a key macronutrient central to the processes of energy and information storage and exchange in the cell. Single-celled photosynthetic organisms, including microalgae, accumulate intracellular reserves of phosphorus (mostly in the form of ...
Alexei Solovchenko
doaj   +2 more sources

Relationship Between Mean Vancomycin Trough Concentration and Mortality in Critically Ill Patients: A Multicenter Retrospective Study

Frontiers in Pharmacology, 2021
Background: It remains unclear whether the mean vancomycin trough concentration (VTC) derived from the entire course of therapy is of potential benefit for critically ill patients.
Yanli Hou, Jiajia Ren, Jiamei Li, Xuting Jin, Ya Gao, Ruohan Li, Jingjing Zhang, Xiaochuang Wang, Xinyu Li, Gang Wang   +9 more
doaj   +1 more source

A 0.6 V 4 GS/s −56.4 dB THD Voltage-to-Time Converter in 28 nm CMOS

IEEE Access, 2022
A 0.6 V voltage-to-time converter (VTC) has been presented in this work for the emerging energy-efficient time-domain circuits and systems. The proposed VTC supports a rail-to-rail input by leveraging shrink sampling with two cascaded voltage sampling ...
Qian Chen, Chirn Chye Boon, Yuan Liang
doaj   +1 more source

Connexin 43 confers chemoresistance through activating PI3K

Oncogenesis, 2022
Circumventing chemoresistance is crucial for effectively treating cancer including glioblastoma, a lethal brain cancer. The gap junction protein connexin 43 (Cx43) renders glioblastoma resistant to chemotherapy; however, targeting Cx43 is difficult ...
Kevin J. Pridham, Farah Shah, Kasen R. Hutchings, Kevin L. Sheng, Sujuan Guo, Min Liu, Pratik Kanabur, Samy Lamouille, Gabrielle Lewis, Marc Morales, Jane Jourdan, Christina L. Grek, Gautam G. Ghatnekar, Robin Varghese, Deborah F. Kelly, Robert G. Gourdie, Zhi Sheng   +16 more
doaj   +1 more source

Semaglutide and Tirzepatide reduce alcohol consumption in individuals with obesity

Scientific Reports, 2023
Alcohol Use Disorder (AUD) contributes significantly to global mortality. GLP-1 (Glucagon-like peptide-1) and GLP-1/GIP (Glucose-dependent Insulinotropic Polypeptide) agonists, FDA-approved for managing type 2 diabetes and obesity, where the former has ...
Fatima Quddos, Zachary Hubshman, Allison Tegge, Daniel Sane, Erin Marti, Anita S. Kablinger, Kirstin M. Gatchalian, Amber L. Kelly, Alexandra G. DiFeliceantonio, Warren K. Bickel   +9 more
doaj   +1 more source

Tidal volume challenge–induced hemodynamic changes can predict fluid responsiveness during one-lung ventilation: an observational study

Frontiers in Medicine, 2023
BackgroundTo evaluate the ability of tidal volume challenge (VTC)-induced hemodynamic changes to predict fluid responsiveness in patients during one-lung ventilation (OLV).Methods80 patients scheduled for elective thoracoscopic surgery with OLV were ...
Yang Zhang, Yinyin Ding, Jiatong Zhang, Tianfeng Huang, Ju Gao   +4 more
doaj   +1 more source

Lateral hypothalamic proenkephalin neurons drive threat-induced overeating associated with a negative emotional state

Nature Communications, 2023
Psychological stressors, like the nearby presence of a predator, can be strong enough to induce physiological/hormonal alterations, leading to appetite changes.
In-Jee You, Yeeun Bae, Alec R. Beck, Sora Shin   +3 more
doaj   +1 more source

A Soluble Platelet-Derived Growth Factor Receptor-β Originates via Pre-mRNA Splicing in the Healthy Brain and Is Upregulated during Hypoxia and Aging

Biomolecules, 2023
The platelet-derived growth factor-BB (PDGF-BB) pathway provides critical regulation of cerebrovascular pericytes, orchestrating their investment and retention within the brain microcirculation. Dysregulated PDGF Receptor-beta (PDGFRβ) signaling can lead
Laura Beth Payne, Hanaa Abdelazim, Maruf Hoque, Audra Barnes, Zuzana Mironovova, Caroline E. Willi, Jordan Darden, Clifton Houk, Meghan W. Sedovy, Scott R. Johnstone, John C. Chappell   +10 more
doaj   +1 more source