Results 151 to 160 of about 201,485 (360)
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
The (In)Security of Smart Cities: Vulnerabilities, Risks, Mitigation, and Prevention
Smart Cities and Innovative Urban Technologies, 2019 In this paper we examine the current state of play with regards to the security of smart city initiatives. Smart city technologies are promoted as an effective way to counter and manage uncertainty and urban risks through the effective and efficient ...
Rob Kitchin, M. Dodge
semanticscholar +1 more source
Ontological model for predicting cyberattacks based on virtualized Honeynets
Logos Ciencia & Tecnología, 2016 The honeynets security tools are widely used today for the purpose of gathering information from potential attackers about vulnerabilities in our network. For performing correct use of them is necessary to understand the existing types, structures raised,
Gaona-García, Pablo +2 more
doaj +1 more source
Astrocyte heterogeneity in brain metastases
Molecular Oncology, EarlyView.Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver +2 more
wiley +1 more source
From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care
Molecular Oncology, EarlyView.Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard +8 more
wiley +1 more source
Author Retains Full Rights AD Cross-Sight Scripting Vulnerabilities [PDF]
, 2014 This paper is from the SANS Institute Reading Room site.
Cross-sight Scripting Vulnerabilities +1 more
core
A Survey of Adversarial Attacks: An Open Issue for Deep Learning Sentiment Analysis Models
Applied SciencesIn recent years, the use of deep learning models for deploying sentiment analysis systems has become a widespread topic due to their processing capacity and superior results on large volumes of information.
Monserrat Vázquez-Hernández +5 more
doaj +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
DETECTING VULNERABILITIES IN CORPORATE NETWORKS [PDF]
, 2021 The main purpose of security systems is to determine vulnerabilities of network. These systems perform extensive research to specify the vulnerabilities that may lead to security policy breaches.
Makhmudov Abdukhalil, Aliyeva Zarina
core
Face Detection Performance Using CNNs and Bug Bonuty Program (BBP)
Iraqi Journal for Computer Science and MathematicsBug bounty schemes make use of outside ethical hackers to find and fix a variety of security flaws, guaranteeing quicker and more affordable problem solving. Better confidence in and image of the company in the cybersecurity space, faster solving issues,
Yasmin Makki Mohialden +2 more
doaj +1 more source