Results 111 to 120 of about 911,238 (315)

Targeting the Vulnerable and the Choice of Vulnerability Measures: Review and Application to Pakistan [PDF]

open access: yes
In this paper, the concept of vulnerability of the poor’s welfare and its practical measures are scrutinised in order to derive implications for targeting poverty reduction policies toward vulnerable households.
Takashi Kurosaki
core  

My Software has a Vulnerability, Should I Worry ? [PDF]

open access: yes, 2013
Vulnerability studies usually rely on the NVD or ‘proof-of-concept’ exploits databases (Exploit-db, or OSVDB), while the individual vulnerability risk is measured by its CVSS score.
Allodi, Luca, Massacci, Fabio
core  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Measuring Vulnerability and Poverty: Estimates for Rural India [PDF]

open access: yes
This paper measures the vulnerability of households in rural India, based upon the ICRISAT panel survey. We employ both ex ante and ex post measures of vulnerability. The latter are decomposed into aggregate and idiosyncratic risks and poverty components.
Imai, Katsushi, Gaiha, Raghav
core  

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Mapping South African farming sector vulnerability to climate change and variability: A subnational assessment [PDF]

open access: yes
"This paper analyzes the vulnerability of South African farmers to climate change and variability by developing a vulnerability index and comparing vulnerability indicators across the nine provinces of the country.
Gbetibouo, Glwadys Aymone   +1 more
core  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Vulnerability: a micro perspective [PDF]

open access: yes
High downside risk to income and livelihoods is part of life in developing countries. Climatic risks, economic fluctuations, and a large number of individual-specific shocks leave these households vulnerable to severe hardship.
Stefan Dercon (QEH)
core  

Mapping Mediterranean bentho‐demersal communities to better inform marine conservation

open access: yesConservation Science and Practice
Marine conservation and spatial planning are seeing increasing interest by stakeholders at the local, regional and international levels to balance biodiversity protection, sustaining fisheries and accommodating new uses of the marine environment.
Miguel López   +4 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

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