Results 101 to 110 of about 911,238 (315)

Analysing vulnerability to volcanic hazards: application to St. Vincent [PDF]

open access: yes, 2010
Volcanology and volcanic risk assessment have in the past been strongly biased towards pure physical sciences and the study of hazard mechanisms. Traditional vulnerability analyses undertaken at volcanoes have focused on the vulnerability of buildings
Lowe, C.J.
core  

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

A conceptual framework to assess vulnerability. Application to global change stressors on South Indian farmers [PDF]

open access: yes
The objectives of the paper are (1) to apply Füssels (2007) conceptual framework of vulnerability to a concrete ongoing research and (2) to discuss on the resulting choice of an adequate vulnerability approach.
Stéphanie Aulong, Robert Kast
core  

On the Economic Vulnerability of Low-Income Countries [PDF]

open access: yes
This paper examines the relevance of the concept of economic vulnerability for low income countries, a topic of recent concern in several international bodies.
Patrick GUILLAUMONT
core   +2 more sources

Calculation model for the thickness limit of high-strength steel-concrete composite structures under the impact of slender thin-walled projectiles

open access: yesBaozha yu Chongji
The study aims to solve the problem of calculating the thickness limit of high-strength steel-concrete composite structures under the impact of slender thin-walled projectiles, a key consideration for protective engineering design.
Qing ZHU   +5 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Commodity Price Volatility, Vulnerability and Development [PDF]

open access: yes
This paper examines the meaning and consequences of the developing countries economic vulnerability to the volatility of commodity prices. It first considers how to define and measure this vulnerability, which has three components, shocks, exposure and ...
Jean-Louis COMBES, Patrick GUILLAUMONT
core  

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Household Vulnerability to Income Poverty [PDF]

open access: yes
This Notes calls for the need to regularly come up with household vulnerability measurements and trends in the Philippines, in addition to official poverty measures, for purposes of guiding policy on poverty concerns.
Albert, Jose Ramon G.
core  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

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