Results 81 to 90 of about 911,238 (315)

Vulnerability to Poverty in select Central Asian Countries [PDF]

open access: yes
In the extant literature either income or consumption expenditures as measured over short periods of time have been regarded as a proxy for the material well-being of households.
Tu Dang, Raghbendra Jha
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Measuring Ethiopian farmers' vulnerability to climate change across regional states: [PDF]

open access: yes
"This study analyzes the vulnerability of Ethiopian farmers to climate change based on the integrated vulnerability assessment approach using vulnerability indicators.
Hassan, Rashid M.   +2 more
core  

Mental health and routine police work: a systematic scoping review

open access: yesHealth & Justice
Background There is increasing attention to the amount of contact between police and those experiencing mental health problems. This includes the amount of time and resource spent by police in attending to calls related to mental health, as well as what ...
Martin Webber   +5 more
doaj   +1 more source

Spatial Distribution of Dissolved Heavy Metals (Hg, Cd, Cu, Pb, Zn) on the Surface Waters of Pare Bay, South Sulawesi

open access: yesIlmu Kelautan, 2019
Pare bay is one of the areas of significance which is utilized for port services, stevedoring, oil distribution, regional industrial development, aquaculture, cultivation and settlement systems.
Ulung Jantama Wisha   +5 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Measuring Vulnerability to Poverty [PDF]

open access: yes
vulnerability, poverty, poverty measurement, C.te d ...
Morduch, Jonathan, Gamanou, Gisele
core  

Vulnerability assessment using remote sensing: The earthquake prone megacity Istanbul, Turkey [PDF]

open access: yes, 2007
Hazards like earthquakes are natural, disasters are not. Disasters result from the impact of a hazard on a vulnerable system or society at a specific location.
Taubenböck, Hannes   +2 more
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Evaluating different approaches to estimating vulnerability [PDF]

open access: yes
A number of researchers have recently proposed a variety of different `vulnerability'measures designed to capture the welfare consequences of risk for poor households, and also proposed a variety of different approaches to estimating these various ...
Ligon, Ethan, Schechter, Laura
core  

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