Results 31 to 40 of about 218,925 (253)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Research on the knowledge graph of accidental explosion damage

Baozha yu Chongji
Constructing a knowledge graph for accidental explosion damage using investigation reports of explosion accident characterized by multi-source, heterogeneous, and overlapping information plays a significant role in data-driven explosion assessment and ...
Jimin WANG, Can JIANG, Bin HAN, Xing WANG, Lei ZHANG   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Impact damage and bearing capacity of CFRP laminates with pretensioned tooth joints and graded thickness

Results in Engineering
This study investigates the impact response and bearing capacity of carbon fiber reinforced polymer (CFRP) laminates with pretensioned tooth joints by integrating experimental and numerical approaches.
Yunqi Ren, Zhaopeng Zhou, Wangjun Ren, Boju Luo, Zhengyuan Yue   +4 more
doaj   +1 more source

SHA512 and MD5 Algorithm Vulnerability Testing Using Common Vulnerability Scoring System (CVSS)

Buana Information Technology and Computer Sciences, 2022
This paper discusses the comparison of the results of testing the OTP (One Time Password) algorithm on two encryptions, namely SHA512 and MD5 which are applied to the Reconciliation Application of the Dinas Pemberdayaan Masyarakat dan Desa Kabupaten ...
Fahmi Basya, Mardi Hardjanto, Ikbal Permana Putra   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Quantitative Robustness for Vulnerability Assessment

Proceedings of the ACM on Programming Languages
Most software analysis techniques focus on bug reachability. However, this approach is not ideal for security evaluation as it does not take into account the difficulty of triggering said bugs. The recently introduced notion of robust reachability tackles this issue by distinguishing between bugs that can be reached
Guillaume Girol, Guilhem Lacombe, Sébastien Bardin   +2 more
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Temperature-effect incorporated damage assessment methodology for beam-slab composite structures subjected to long-duration blast loads

Defence Technology
Aiming at addressing the issues of unclear dynamic response mechanisms and insufficient quantification of temperature coupling effects in building structures under long-duration blast loads, this study investigates typical composite beam-slab structures ...
Wei Liu, Wei Wang, Zhenyu Lu, Baoding Li, Bin Zhang, Bo Gao, Xucai Wang, Gang Peng, Benjun Shi   +8 more
doaj   +1 more source