Results 41 to 50 of about 900,479 (294)

Seismic vulnerability of churches in Faial and Pico islands, Azores [PDF]

open access: yes, 2012
Earthquakes represent one of the main cause of serious damage and loss of historic and architectural heritage. Interventions to preserve these building should start with a careful knowledge and assessment of their seismic vulnerability, in order to ...
Costa, A.   +6 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Impact damage and bearing capacity of CFRP laminates with pretensioned tooth joints and graded thickness

open access: yesResults in Engineering
This study investigates the impact response and bearing capacity of carbon fiber reinforced polymer (CFRP) laminates with pretensioned tooth joints by integrating experimental and numerical approaches.
Yunqi Ren   +4 more
doaj   +1 more source

Seismic and Coastal Vulnerability Assessment Model for Buildings in Chile

open access: yesBuildings, 2021
This article proposes a vulnerability assessment model for evaluating buildings’ expected seismic performance, as well as their vulnerability to tsunamis.
Catalina Quiñones-Bustos   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Unified Approach For Organizational Network Vulnerability Assessment

open access: yes, 2013
The present business network infrastructure is quickly varying with latest servers, services, connections, and ports added often, at times day by day, and with a uncontrollably inflow of laptops, storage media and wireless networks.
Jagli, Mrs. Dhanamma   +1 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Temperature-effect incorporated damage assessment methodology for beam-slab composite structures subjected to long-duration blast loads

open access: yesDefence Technology
Aiming at addressing the issues of unclear dynamic response mechanisms and insufficient quantification of temperature coupling effects in building structures under long-duration blast loads, this study investigates typical composite beam-slab structures ...
Wei Liu   +8 more
doaj   +1 more source

Unknown Vulnerability Risk Assessment Based on Directed Graph Models: A Survey

open access: yesIEEE Access, 2019
Nowadays, vulnerability attacks occur frequently. Due to the information asymmetry between attackers and defenders, vulnerabilities can be divided into known and unknown.
Wenhao He, Hongjiao Li, Jinguo Li
doaj   +1 more source

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