Results 81 to 90 of about 158,542 (263)

Dependence of the vulnerability index on the heart cycle length

Physiological Research, 2007
Index of vulnerability is a parameter based on ventricular gradient evaluating the risk of arrhythmia development. The index is derived from isointegral maps of the QT interval. Individual characteristics of isointegral maps are influenced by different factors, which contribute to the relatively high variability among measured parameters of maps in ...
J, Martinka, K, Kozlíková
openaire   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Rapid Seismic Vulnerability Assessment of Buildings in the Old Algiers

Journal of Materials and Engineering Structures, 2020
The selection of an appropriate seismic vulnerability method to evaluate buildings stock in urban area depends essentially on the available information. Information about buildings can be obtained essentially from field visual inspection. In this context,
Farah LAZZALI, Mohammed N. FARSI
doaj  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

PEMETAAN KERENTANAN SEISMIK MELALUI ANALISIS MIKROTREMOR HVSR DI WILAYAH KECAMATAN KEMILING DAN SEKITARNYA

JGE
Wilayah Kemiling yang terletak di Kota Bandar Lampung sering kali mengalami gempa lokal dengan magnitudo kecil. Gempa ini terjadi secara berulang dan dirasakan di daerah Kemiling dan sekitarnya.
Agus Ariyanto, Alhada Farduwin, Yudha Styawan, Intan Andriani Putri, Wahyu Eko Junian, Nugroho Prasetyo, Reza Rizki, Rizki Wulandari   +7 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Development of an agricultural drought vulnerability index for risk assessment, insurance pricing, and disaster management through Google Earth engine

Discover Geoscience
This study presents an implementation of the Agricultural Drought Vulnerability Index (ADVI) using Google Earth Engine to assess drought vulnerability in semi-arid agricultural regions.
Shemin T John, Merin Susan Philip
doaj   +1 more source

Coastal Management: A Review of Key Elements for Vulnerability Assessment

Journal of Marine Science and Engineering
Damaging and accelerated anthropization in coastal areas, as well as the need to adapt to climate change, means we must concentrate on improving management plans based on the diagnoses provided by coastal studies. Among these studies is the vulnerability
Cesia J. Cruz-Ramírez, Valeria Chávez, Rodolfo Silva, Juan J. Muñoz-Perez, Evelia Rivera-Arriaga   +4 more
doaj   +1 more source

Fuzzy Vulnerability Index

Abstract This paper introduces the Fuzzy Vulnerability Index (FVI), an innovative toolfor socioeconomic assessment that employs advanced computational methods,including artificial intelligence (AI) and fuzzy logic algorithms. The FVI providesa multidimensional analysis of household challenges across education, housing,and health dimensions.
openaire   +1 more source