Results 71 to 80 of about 581,731 (308)

Using productivity and susceptibility indices to assess the vulnerability of United States fish stocks to overfishing [PDF]

, 2010
Assessing the vulnerability of stocks to fishing practices in U.S. federal waters was recently highlighted by the National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric Administration, as an important factor to consider when 1 ...
Bigelow, Keith, Cope, Jason, Cortés, Enric, Field, John, Gedamke, Todd, Kobayashi, Donald, Lawson, Peter, Link, Jason, Ormseth, Olav, Overholtz, William, Patrick , Wesley S., Spencer , Paul   +11 more
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Checkpoint blockade and the stem‐like T cell trade‐off

Molecular Oncology, EarlyView.
Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley   +1 more source

Indice de vulnerabilidad estructural ante los efectos de remoción en masa en edificaciones de mampostería basado en conjuntos difusos Structural vulnerability index to the effects of landslides in masonry buildings based on fuzzy sets

Revista Ingeniería de Construcción, 2012
En este trabajo se presenta un modelo rápido y sencillo de evaluación de la vulnerabilidad estructural de edificaciones a escala regional. El modelo fue construido de forma que puede ser aplicado especialmente a zonas donde no se cuenta con información ...
Esperanza Maldonado Rondón, Gustavo Chio Cho   +1 more
doaj  

A Framework for Effective Multi-Hazard Risk Assessment in Post-Mining Areas

Safety
This work presents a structured methodology for multi-hazard risk assessment in post-mining coal areas, addressing the complex interactions between natural, mining, and technological hazards.
Dafni M. Nalmpant-Sarikaki, Alexandros I. Theocharis, Nikolaos C. Koukouzas, Ioannis E. Zevgolis   +3 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Assessment of Farm Vulnerability to Climate Change in Southern France

Land
Climate change (CC) is a major threat to agriculture, the sector that supports the territorial economy in the Pays Haut Languedoc et Vignoble (PHLV) region (south France).
Abderraouf Zaatra, Mélanie Requier-Desjardins, Hélène Rey-Valette, Thierry Blayac, Hatem Belhouchette   +4 more
doaj   +1 more source

Regional Vulnerability : The Case of East Asia [PDF]

In a case study of six East Asian economies, we use dynamic factor analysis to estimate a regional component of the exchange market pressure index (EMPI) as a measure of regional financial stress.
Mody, Ashoka, Taylor, Mark P.
core  

Proposed Occupational Vulnerability Index COVID-19

Occupational Diseases and Environmental Medicine, 2020
[EN] Introduction: Vulnerable is someone who can be hurt or receive injury, physically or morally. The work environment appears as one of the dimensions in which social vulnerability develops and social and occupational vulnerability is defined. The literature does not include an assessment of quantified occupational vulnerability as it already exists ...
Vicente-Herrero, Mª Teófila, Ramírez Íñiguez de la Torre, Mª Victoria, Del Campo Balsa, Mª Teresa, Reinoso Barbero, Luis, Rueda Garrido, Juan Carlos, Santamaria Navarro, Cristina   +5 more
openaire   +3 more sources

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source