Results 151 to 160 of about 76,465 (345)

Retraction: Overexpressed miR‐335‐5p Reduces Atherosclerotic Vulnerable Plaque Formation in Acute Coronary Syndrome

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
RETRACTION: Sun D. Ma T. Zhang Y. Zhang F. Cui B. Overexpressed miR‐335‐5p Reduces Atherosclerotic Vulnerable Plaque Formation in Acute Coronary Syndrome Journal of Clinical Laboratory Analysis 35, no. 2 (2021): e23608 https://doi.org/10.1002/jcla.23608 The above article, published online on 5 December 2020 in Wiley Online Library (http://onlinelibrary.
wiley   +1 more source

Microglial States Are Susceptible to Senescence and Cholesterol Dysregulation in Alzheimer's Disease

open access: yesAging Cell, EarlyView.
Senescent microglia in Alzheimer's disease exhibit dysregulated cholesterol metabolism and express Disease‐Associated Microglia (DAM) signatures, including inflammatory and phagocytic markers. Single‐nucleus RNA‐seq from human brain tissues identified cholesterol‐related senescence gene co‐expression modules linked to microglial senescence.
Boyang Li   +8 more
wiley   +1 more source

Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra   +3 more
wiley   +1 more source

Asparaginase and Autophagy Inhibitors Effectively Remove Senescent Cells by Synergistically Limiting Asparagine Supply

open access: yesAging Cell, EarlyView.
A model of cellular asparagine source and AH treatment kills senescent cells effectively and selectively. In senescent cells, there is a defect in ASNS. Treatment with ASNase to deplete extracellular Asn, combined with HCQ to inhibit autophagy‐derived Asn, results in a severe depletion of Asn and subsequent senescent cell death.
Zhihua Huang   +10 more
wiley   +1 more source

Dietary Citrate Restores Age‐Related Endothelial Cell Mitochondrial Dysfunction and Alleviates Atherosclerosis

open access: yesAging Cell, EarlyView.
Citrate, as a common food additive, provides the major cellular ATP source. This study demonstrates that dietary citrate attenuates common vascular diseases, including atherosclerosis and hypertension, and reduces frailty in mice by delaying vascular aging.
Ya Zhao   +11 more
wiley   +1 more source

Intracoronary Imaging of Vulnerable Plaque-From Clinical Research to Everyday Practice. [PDF]

open access: yesJ Clin Med, 2022
Legutko J   +8 more
europepmc   +1 more source

Plasma apolipoproteins and memory function in alcohol use disorder: Findings in male C57BL/6J mice and men suggest a role for APOAI

open access: yesAlcohol, Clinical and Experimental Research, EarlyView.
Both alcohol‐dependent mice and abstinent AUD patients exhibited elevated plasma APOAI levels and memory impairments compared to controls. Higher APOAI levels were associated with poorer memory in both species, suggesting its potential as a biomarker for alcohol‐related cognitive deficits.
Berta Escudero   +5 more
wiley   +1 more source

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