Results 131 to 140 of about 33,556 (247)

Small‐Molecule Kinase Inhibitors Modulating Circadian Rhythms

Medicinal Research Reviews, EarlyView.
ABSTRACT The circadian clock mechanism generates 24‐h rhythms crucial for regulating various physiological processes, and its dysregulation has been implicated in numerous diseases. In cells, the circadian clock operates through a transcriptional‐translational feedback loop, where phosphorylation plays a pivotal role in maintaining accurate circadian ...
Irene Castellino, Manuela Bartolini, Rudolf Andrys, Kamil Musilek   +3 more
wiley   +1 more source

Monocyte-Differentiation-Activated Fluorescent "Scout" Probe for Precise in Vivo Detection of Vulnerable Plaque. [PDF]

Adv Sci (Weinh)
Li Z, Dong J, Liu Z, Zhang C, Li J, Tao Y, Yang D, Liu Y, Chen H, Liu L, Ji J, Cao F, Ding D, Liu Q, Fu C, Guo W.   +15 more
europepmc   +1 more source

Plasma asymmetric dimethylarginine is associated with vulnerable plaque and long-term outcomes in stable coronary artery disease. [PDF]

Sci Rep, 2023
Huang SS, Huang WC, Tsai CT, Chen YY, Lee SH, Lu TM.   +5 more
europepmc   +1 more source

Circadian rhythms and chronotherapy in Alzheimer's disease: Mechanisms and therapeutic implications

Neuroprotection, EarlyView.
Circadian dysregulation contributes to Alzheimer's disease through sleep disruption, clock‐gene dysfunction, neuroinflammation, impaired proteostasis, and metabolic imbalance. These alterations promote cognitive decline and disease progression, while circadian biomarkers and chronotherapeutic interventions offer opportunities for precision diagnosis ...
Bivek Singh, Filippo Pigazzani, Roberto Manfredini   +2 more
wiley   +1 more source

Intensive lipid-lowering therapy-related regression of a vulnerable plaque confirmed by serial optical coherence tomography: a case report. [PDF]

Front Cardiovasc Med
Qu J, Liu K, Johnson N, Wagatsuma K, Su Y, Du B, He Y.   +6 more
europepmc   +1 more source

Current advances in the imaging of atherosclerotic vulnerable plaque using nanoparticles. [PDF]

Mater Today Bio, 2022
Zhang M, Xie Z, Long H, Ren K, Hou L, Wang Y, Xu X, Lei W, Yang Z, Ahmed S, Zhang H, Zhao G.   +11 more
europepmc   +1 more source

A Possible Case of Temporomandibular Joint Dislocation, Trepanation, and Metabolic Bone Disease in a Young Adolescent From North‐Central Myanmar (1000–700 bce)

International Journal of Osteoarchaeology, EarlyView.
ABSTRACT This osteobiography explores the life history of an adolescent who lived during the early‐mid Bronze Age (c. 1000–700 bce) and was buried at Nyaung'gan, a site in north‐central Myanmar. Burial 3b had multiple skeletal lesions, and their bones were covered in well‐remodeled subperiosteal new bone.
Anna Willis, Baptiste Pradier, Thu Thu Win, T. O. Pryce   +3 more
wiley   +1 more source

OCT-based vulnerable plaque features and MACE prediction in premature coronary artery disease. [PDF]

Front Cardiovasc Med
Liu J, Meng H, Chen L, Wang L, Xu J.
europepmc   +1 more source

Lower attenuation and higher kurtosis of coronary artery calcification associated with vulnerable plaque - an agatston score propensity-matched CT radiomics study. [PDF]

BMC Cardiovasc Disord, 2023
Huang EP, Lin HS, Chen YC, Li YH, Huang YL, Ju YJ, Yu HC, Kicska GA, Wu MT.   +8 more
europepmc   +1 more source

Plant responses to iron nutrition with emphasis on the underutilized crop tef (Eragrostis tef): A review

PLANTS, PEOPLE, PLANET, EarlyView.
Iron (Fe) deficiency limits the physical health, cognitive development, and economic output of billions of people globally, especially children and productive‐age women. Tef is an underutilized and stress‐resilient crop, which is becoming popular for its grains containing high bioavailable Fe and has the potential to mitigate Fe deficiency.
Muhammad Numan, David Remington, Ayalew Ligaba‐Osena   +2 more
wiley   +1 more source