Results 151 to 160 of about 33,556 (247)

Human brain matters: Navigating the neuropathology of COVID‐19

Brain Pathology, EarlyView.
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland, Angelica Scaramuzza, Marianna Bugiani, Wilma D. J. van de Berg, Jinte Middeldorp   +4 more
wiley   +1 more source

Perspectives in the Diagnosis, Clinical Impact, and Management of the Vulnerable Plaque. [PDF]

J Clin Med
Alperi A, Antuna P, Almendárez M, Álvarez R, Del Valle R, Pascual I, Hernández-Vaquero D, Avanzas P.   +7 more
europepmc   +1 more source

Preventive percutaneous coronary intervention versus optimal medical therapy for vulnerable plaque: a meta-analysis. [PDF]

BMC Cardiovasc Disord
Chen Y, Liu X, Qiu Y, Guo Q, Zhang F, Nie S, Liu H, Long D, Wang X.   +8 more
europepmc   +1 more source

Establishment of a Novel Mouse Model for Atherosclerotic Vulnerable Plaque. [PDF]

Front Cardiovasc Med, 2021
Wang X, Fu Y, Xie Z, Cao M, Qu W, Xi X, Zhong S, Piao M, Peng X, Jia Y, Meng L, Tian J.   +11 more
europepmc   +1 more source

Distinctly altered TRPC3 and TRPC6 expression patterns in human Alzheimer's disease cortex and hippocampus

Brain Pathology, EarlyView.
Divergent remodeling of TRPC channels occurs in Alzheimer's disease, with TRPC3 increased in neurons and reactive astrocytes and TRPC6 reduced in pyramidal neurons. These alterations may contribute to calcium dysregulation, neuroinflammation, and synaptic dysfunction during AD progression.
Xingyong Chen, Zhengjun Wang, Jiaxing Wang, Dehui Kong, Xusheng Wang, Lu Lu, Peter T. Nelson, Fu‐Ming Zhou, Francesca‐Fang Liao   +8 more
wiley   +1 more source

Inflammation mediates the relationship between cardiometabolic index and vulnerable plaque in patients with acute coronary syndrome. [PDF]

Lipids Health Dis
Yan H, Lv S, Pi H, Yu H, Yin W, Wang Y, Lan Y, Liu W.   +7 more
europepmc   +1 more source

Safety and Efficacy of Drug-Coated Balloons in Patients with Acute Coronary Syndromes and Vulnerable Plaque. [PDF]

Clin Appl Thromb Hemost, 2022
Zhang YB, Liu HD, Xing JH, Chen BW, Zhao YY, Gu HP, Tao HL.   +6 more
europepmc   +1 more source

Clinicopathological and molecular heterogeneity of amyloid‐β in unnatural deaths under 70 years: A forensic autopsy–based study

Brain Pathology, EarlyView.
This study investigates amyloid‐beta (Aβ) pathology in a forensic autopsy cohort of relatively young individuals (40–69 years). Using detailed immunohistochemical analyses of multiple Aβ species, we demonstrate marked regional and molecular heterogeneity, particularly within the striatum.
Shojiro Ichimata, Yukiko Hata, Koji Yoshida, Ryo Tanaka, Shigeo Murayama   +4 more
wiley   +1 more source

Cardiovascular toxicity from immune checkpoint inhibitor therapy: an inflammatory continuum

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI) therapy has markedly improved outcomes in advanced malignancies but has also revealed a distinct spectrum of cardiovascular immune‐related adverse events. Myocarditis represents the most severe manifestation, while non‐inflammatory left ventricular dysfunction and vascular inflammation have emerged as additional ...
Fabrice Reyes, Florian Buehning, Tobias Lerchner, Julia Vogel, Raluca I. Mincu, Matthias Totzeck, Tienush Rassaf, Lars Michel   +7 more
wiley   +1 more source

Machine Learning for Evaluating Vulnerable Plaque on Coronary Computed Tomography Using Spectral Imaging. [PDF]

Circ Rep
Mochizuki J, Hata Y, Nakaura T, Hashimoto K, Uetani H, Nagayama Y, Kidoh M, Funama Y, Hirai T.   +8 more
europepmc   +1 more source