Results 141 to 150 of about 78,688 (294)

Psychodermatology of the Female: Hormones, Skin and Mental Health Across the Lifespan

JEADV Clinical Practice, EarlyView.
Hormonal transitions across the female lifespan shape skin disease and psychiatric comorbidity through the brain–skin axis and Neuro‐Immuno‐Cutaneous‐Endocrine (NICE) network. This narrative review links puberty, menstruation, pregnancy, postpartum and menopause to dermatologic and psychosocial outcomes.
Sheila Sharifi, Jessica Gulati, Veranca Shah, Keira Barr, Mohammad Jafferany   +4 more
wiley   +1 more source

Commentary on “Preventive percutaneous coronary intervention versus optimal medical therapy alone for the treatment of vulnerable atherosclerotic coronary plaques (PREVENT): a multicenter, open-label, randomized controlled trial”

Bleeding, Thrombosis and Vascular Biology
To address the potential risk of acute coronary syndrome, the current clinical guidelines on coronary artery diseases recommend revascularization in significant and flow-limiting lesions, but emerging data depict vulnerable atherosclerotic coronary ...
Ottavia Borghese, Claudio Vincenzoni
doaj   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

Med Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang, Ge Zhang, Tian‐Ding Liu, Tianshu Gu, Fengyi Yu, Pengyuan Xu, Wunan Mi, Xuanjiang Zhao, Qian Guo, Honglin Zheng, Taiqi Zhao, Qiang Li, Di Lu, Mingxuan Duan, Chaoyang Yu, Ruhao Wu, Shiqian Zhang, Haonan Zhang, Zeyu Wang, Youyang Zheng, Yan Xiao, Zenglei Zhang, Ge Zhang   +22 more
wiley   +1 more source

White Adipose Tissue Browning and Cross Talk With Metabolic Diseases and Tumors: From Molecular Mechanisms to Clinical Translation

Med Research, EarlyView.
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang, Diyuan Zhang, Yuqin Zhou, Ling Qian, Yan Wang, Lei Peng, Min Zhao, Hao Tian, Zhenyu Wu, Aiqi Tang, Minghao Sun, Yi Zhang, Xiaowei Qi   +12 more
wiley   +1 more source

Rapid Progression of a CT-Defined Vulnerable Coronary Plaque: A Multimodality Imaging Case Report

Case Reports in Cardiology
Rapid progression of vulnerable plaques due to intraplaque neovascularization and hemorrhage is deemed as an important process preceding plaque rupture leading to myocardial infarction.
B. S. H. Hagen, P. A. Diemen, M. J. Bom, S. P. Schumacher, A. C. van Rossum, A. Nap, M. P. Opolski, C. J. W. Verouden, I. Danad, P. Knaapen   +9 more
doaj   +1 more source

Retracted: Analysis of Predictive Model of Coronary Vulnerable Plaque under Hemodynamic Numerical Simulation. [PDF]

J Healthc Eng, 2023
Healthcare Engineering JO.
europepmc   +1 more source

Inflammation, Immunity, and Cardiovascular Diseases

Med Research, EarlyView.
Cardiovascular stress signals (e.g., hemodynamic shear, oxidized lipids, and ischemia) act on endothelial and immune cells to activate and amplify inflammation through NF‐κB, the NLRP3 inflammasome, and JAK/STAT signaling, inducing proinflammatory cytokines/chemokines (IL‐6, IL‐1β, TNF‐α, and CCL2) and self‐amplifying circuits; clinically, inflammatory
Dezhi Guo, Yan Liao, Rui Zhao, Zhaoyu Li, Kaikai Wang, Haoling Zhang, Pingxin Sun, Yadong Guo, Wangzheqi Zhang   +8 more
wiley   +1 more source

Single‐nucleotide polymorphisms in coronary artery disease: Biological complexity, risk architecture, and implications for precision prevention

Precision Medical Sciences, EarlyView.
This graphical summary highlights the clinical application of single‐nucleotide polymorphisms‐based risk stratification in coronary artery disease. By integrating polygenic risk with clinical assessment, imaging, and preventive strategies, genetic information enables earlier risk identification, optimized screening, and personalized lifestyle and ...
Li Dai, Mosi Chen, Jun Hu, Lei Huang, Ye Yang, Chang Chen, Ying Zhuang, Yan Pan, Bingjun Qian   +8 more
wiley   +1 more source

Fractional flow reserve versus intravascular ultrasound guidance for percutaneous coronary intervention in intermediate coronary stenoses: A systematic review and meta‐analysis

Precision Medical Sciences, EarlyView.
Fractional Flow Reserve versus Intravascular Ultrasound for guiding percutaneous coronary intervention in coronary artery disease: A systematic review and meta‐analysis of 5 studies (over 3,900 patients) showing comparable outcomes in MACE, mortality, and target vessel revascularization.
Sanket Patel, Mirza Muhammad Hadeed Khawar, Mehwish Safdar, Iman Ahsan, Rahul Kumar, Promise Ebube Mbala, Mustafa Abrar Zaman, Salma Frindou, Sabahat Kanwal, Mohammad Issa Ayash, Thomas Viji Pulickal, Sonika Gopathoti, Sai Erambalur, Lima Dalil   +13 more
wiley   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source