Results 111 to 120 of about 78,688 (294)

Reduced Necrosis and Content of Apoptotic M1 Macrophages in Advanced Atherosclerotic Plaques of Mice With Macrophage-Specific Loss of Trpc3 [PDF]

, 2017
In previous work we reported that ApoeKO mice transplanted with bone marrow cells deficient in the Transient Receptor Potential Canonical 3 (TRPC3) channel have reduced necrosis and number of apoptotic macrophages in advanced atherosclerotic plaques ...
Birnbaumer, Lutz, Dube, Prabhatchandra R., Solanki, Sumeet, Vazquez, Guillermo   +3 more
core   +1 more source

Influence of the Residual Gensini Score on Prognosis of Patients With ST‐Elevation Myocardial Infarction

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background The residual Gensini score (rGS) was developed to quantify the severity of coronary atheroma burden after coronary revascularisation. The predictive value of the rGS for clinical outcomes in patients with ST‐segment elevation myocardial infarction (STEMI) remains unexplored.
Batric Popovic, Nassima Djaballah, Mirela Tomic, Renaud Fay, Victorine Fraichot, Florian Eggenspieler, Pierre Adrien Metzdorf, Jeanne Varlot, Edoardo Camenzind   +8 more
wiley   +1 more source

Orthopedic surgery increases atherosclerotic lesions and necrotic core area in ApoE-/- mice [PDF]

, 2016
Background and aims Observational studies show a peak incidence of cardiovascular events after major surgery. For example, the risk of myocardial infarction increases 25-fold early after hip replacement.
Chen, Cohen, Corrales-Medina, Dutta, Dutta, Gualandro, Hans W.M. Niessen, Hanson, Ilse P.A. Zethof, Janssen, Kaynar, King, Kleemann, Lalmohamed, Landesberg, Lars F.H. Theyse, Libby, Martine C. Morrison, Moore, Morrison, Naghavi, Paul A.J. Krijnen, Reid, Rianne van der Linden, Robert Kleemann, Santos-Gallego, Santos-Gallego, Santos-Gallego, Seimon, Smeeth, Tan, Thompson, Thompson, Van der Donckt, van Dijk, Virmani, Virmani, Wessel W. Fuijkschot, Yvo M. Smulders, Zhang   +39 more
core   +2 more sources

Financial Toxicity Associated with Biological Medicines: A Scoping Review

Clinical Pharmacology &Therapeutics, EarlyView.
Financial toxicity, defined as the economic burden experienced by patients due to medication and other healthcare costs and their consequences, such as material, psychosocial and behavioral effects, represents a significant concern for individuals receiving biological medicines.
Laura Sara Maria Saarukka, Kamilla Yamileva, Kari Linden, Anniina Simonen, Anna‐Riia Holmström   +4 more
wiley   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Bayesian semiparametric inference for multivariate doubly-interval-censored data [PDF]

, 2010
Based on a data set obtained in a dental longitudinal study, conducted in Flanders (Belgium), the joint time to caries distribution of permanent first molars was modeled as a function of covariates.
De Iorio, Maria, Jara, Alejandro, Lesaffre, Emmanuel, Quintana, Fernando   +3 more
core   +4 more sources

Vulnerable atherosclerotic plaques

Medical academic journal, 2009
The initial pathogenesis moment in development of an acute sharp coronary thrombosis is break, so-called vulnerable atherosclerotic plaque. The combination of an inflammation, distraction a collagenic skeleton, refind tire covers plaque and a spasm of arteries leads to break of a surface plaque therefore process thrombogenesis is started, leading ...
E J Naumova, E S Naumov
openaire   +1 more source

Connecting the dots: A narrative review of the relationship between heart failure and cognitive impairment

ESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi, Maria Giulia Bellicini, Marianna Adamo, Andrea Pilotto, Marco Metra, Alessandro Padovani, Riccardo Proietti   +6 more
wiley   +1 more source

The effect of serum MMP⁃9 and IL⁃6 on the vulnerability of carotid atherosclerotic plaque

Chinese Journal of Contemporary Neurology and Neurosurgery, 2012
Objective To explore the relationship of MMP⁃9 and IL⁃6 and the vulnerability of carotid atherosclerotic plaque. Methods According to the plaque vulnerability, 69 patients with acute cerebral infarction were divided into vulnerable plaque group (n = 35 ...
Wei WANG, Yu⁃qin CHE, Yuan⁃yuan WANG, Jian⁃hua FAN, Hong⁃yan ZHANG, Hui LV   +5 more
doaj  

Biomarkers in acute coronary syndromes and their role in diabetic patients [PDF]

, 2005
Diabetic patients with acute coronary syndromes are at high risk for cardiovascular complications but risk stratification in these patients remains challenging.
Christopher Heeschen, Heeschen C, James SK, Khaliq A, Luttun A, Mak KH   +5 more
core   +1 more source