Novel Metal-Free Nanozyme for Targeted Imaging and Inhibition of Atherosclerosis via Macrophage Autophagy Activation to Prevent Vulnerable Plaque Formation and Rupture. [PDF]
Wang L +10 more
europepmc +1 more source
Early identification of carotid vulnerable plaque in asymptomatic patients. [PDF]
Jiao Y +6 more
europepmc +1 more source
Stimulating proteasomal degradation in human proteinopathies
The proteasome mediates the degradation of a wide range of proteins. Boosting proteasomal degradation may be beneficial in several disease contexts and can be achieved either by modulating proteasome activity or by improving substrate delivery. Proteasome activity can be enhanced by increasing proteasome abundance, inducing constitutive gate opening ...
Maria E. Gierisch +2 more
wiley +1 more source
Analysis of Predictive Model of Coronary Vulnerable Plaque under Hemodynamic Numerical Simulation.
Song Q, Chen M, Shang J, Hu Z, Cai H.
europepmc +1 more source
Combating ageing beyond the cell: Emerging roles of extracellular proteostasis
Ageing challenges the body's ability to maintain a stable and functional proteome, leading to protein damage and aggregation both inside and outside cells. This review focuses on the less well understood mechanisms of extracellular protein quality control and how they become disrupted in ageing, particularly in neurodegenerative diseases.
Siddharth R. Venkatesh +7 more
wiley +1 more source
Vulnerable Plaques, Vulnerable Patients, and Intravascular Imaging
Gregg W, Stone +2 more
openaire +2 more sources
Vulnerable plaque features and adverse events in patients with diabetes mellitus: a post hoc analysis of the COMBINE OCT-FFR trial. [PDF]
Del Val D +12 more
europepmc +1 more source
In vivo imaging of vulnerable plaque with intravascular modalities: its advantages and limitations. [PDF]
Kitahara S +6 more
europepmc +1 more source
Grading in Gerodontology: A Framework
ABSTRACT Introduction Understanding and anticipating oral health deterioration in older adults requires more than describing their current oral and general health. Risk factors arising from oral, systemic and social domains strongly influence disease progression, care complexity and the ability to maintain function over time.
Falk Schwendicke +27 more
wiley +1 more source
CircHIPK3 targets DRP1 to mediate hydrogen peroxide-induced necroptosis of vascular smooth muscle cells and atherosclerotic vulnerable plaque formation. [PDF]
Li X +9 more
europepmc +1 more source

