Results 181 to 190 of about 33,556 (247)

Early identification of carotid vulnerable plaque in asymptomatic patients. [PDF]

open access: yesBMC Cardiovasc Disord, 2020
Jiao Y   +6 more
europepmc   +1 more source

Stimulating proteasomal degradation in human proteinopathies

open access: yesThe FEBS Journal, EarlyView.
The proteasome mediates the degradation of a wide range of proteins. Boosting proteasomal degradation may be beneficial in several disease contexts and can be achieved either by modulating proteasome activity or by improving substrate delivery. Proteasome activity can be enhanced by increasing proteasome abundance, inducing constitutive gate opening ...
Maria E. Gierisch   +2 more
wiley   +1 more source

Combating ageing beyond the cell: Emerging roles of extracellular proteostasis

open access: yesThe FEBS Journal, EarlyView.
Ageing challenges the body's ability to maintain a stable and functional proteome, leading to protein damage and aggregation both inside and outside cells. This review focuses on the less well understood mechanisms of extracellular protein quality control and how they become disrupted in ageing, particularly in neurodegenerative diseases.
Siddharth R. Venkatesh   +7 more
wiley   +1 more source

Vulnerable Plaques, Vulnerable Patients, and Intravascular Imaging

open access: yesJournal of the American College of Cardiology, 2018
Gregg W, Stone   +2 more
openaire   +2 more sources

Vulnerable plaque features and adverse events in patients with diabetes mellitus: a post hoc analysis of the COMBINE OCT-FFR trial. [PDF]

open access: yesEuroIntervention
Del Val D   +12 more
europepmc   +1 more source

In vivo imaging of vulnerable plaque with intravascular modalities: its advantages and limitations. [PDF]

open access: yesCardiovasc Diagn Ther, 2020
Kitahara S   +6 more
europepmc   +1 more source

Grading in Gerodontology: A Framework

open access: yesGerodontology, EarlyView.
ABSTRACT Introduction Understanding and anticipating oral health deterioration in older adults requires more than describing their current oral and general health. Risk factors arising from oral, systemic and social domains strongly influence disease progression, care complexity and the ability to maintain function over time.
Falk Schwendicke   +27 more
wiley   +1 more source

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