Results 51 to 60 of about 2,628,839 (264)

An electronic registry to improve adherence to active surveillance monitoring among men with prostate cancer at a safety-net hospital: protocol for a pilot study

Pilot and Feasibility Studies, 2019
Background The evidence-based practice of active surveillance to monitor men with favorable-risk prostate cancer in lieu of initial definitive treatment is becoming more common. However, there are barriers to effective implementation, particularly in low-
Benjamin Cedars, Sarah Lisker, Hala T. Borno, Puneet Kamal, Benjamin Breyer, Urmimala Sarkar   +5 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Emergency preparedness for vulnerable populations

, 2023
This paper seeks to understand the current relationship between emergency preparedness and vulnerable populations. Vulnerable populations refer to individuals with physical, cognitive, or sensory disadvantages as well as individuals in low-income housing/

core  

Utilization of the Behavior Change Wheel framework to develop a model to improve cardiometabolic screening for people with severe mental illness

Implementation Science, 2017
Background Individuals with severe mental illness (e.g., schizophrenia, bipolar disorder) die 10–25 years earlier than the general population, primarily from premature cardiovascular disease (CVD).
Christina Mangurian, Grace C. Niu, Dean Schillinger, John W. Newcomer, James Dilley, Margaret A. Handley   +5 more
doaj   +1 more source

mHealth app using machine learning to increase physical activity in diabetes and depression: clinical trial protocol for the DIAMANTE Study

BMJ Open, 2020
Introduction Depression and diabetes are highly disabling diseases with a high prevalence and high rate of comorbidity, particularly in low-income ethnic minority patients.
Urmimala Sarkar, Jing Xu, Bibhas Chakraborty, Adrian Aguilera, Caroline A Figueroa, Rosa Hernandez-Ramos, Anupama Cemballi, Laura Gomez-Pathak, Jose Miramontes, Elad Yom-Tov, Xiaoxi Yan, Arghavan Modiri, Jai Aggarwal, Joseph Jay Williams, Courtney R Lyles   +14 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

How Researchers Define Vulnerable Populations in HIV/AIDS Clinical Trials [PDF]

, 2010
In this study, we interviewed researchers, asking them to define vulnerable populations in HIV/AIDS clinical trials, and provide feedback on the federal regulations for three vulnerable populations.
Ronald P. Strauss, Sengupta, Sohini, Bernard Lo, Joseph Eron, Eron, Joseph, Lo, Bernard, Allen L. Gifford, Strauss, Ronald P., Sohini Sengupta, Gifford, Allen L.   +9 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Working with vulnerable populations

, 2015
We discuss key issues to consider when conducting clinical trials with vulnerable children, youths, and families, with particular attention to groups affected by communal violence/war and families affected by HIV/AIDS.
Fredrick Kanyanganzi, Catherine Kirk, Moses Zombo, Morris Munyana, Katrina Hann, Theresa S. Betancourt, Christine Mushashi, William Beardslee, Justin I. Bizimana   +8 more
core   +1 more source