Results 71 to 80 of about 2,628,839 (264)

Complementary medicine among individuals experiencing homelessness in Switzerland: a quantitative and qualitative descriptive study

BMC Complementary Medicine and Therapies
Background People experiencing homelessness (PEH) are disproportionately affected by health issues yet remain underserved by the health care system. Emerging findings suggest that complementary medicine (CM) approaches might help address the low access ...
Véronique S. Grazioli, Evelyne Hangartner, Patrick Bodenmann, Luana Schaad, Léa Grosjean, Justin Nikles, David J. T. Campbell, Laurent Hyvert, Tshahé Anongba Varela, Susan E. Collins, Caroline Leblanc, Christine Loignon, Chantal Berna   +12 more
doaj   +1 more source

An Efficient Gatekeeper Algorithm for Detecting GxE

Cancer Informatics, 2010
The risk for many complex diseases is believed to be a result of the interactive effects of genetic and environmental factors. Developing efficient techniques to identify gene-environment interactions (GxE) is important for unraveling the etiologic basis
Jimmy T. Efird
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Arizona\u27s Vulnerable Populations [PDF]

, 2014
Arizona’s vulnerable populations are struggling on a daily basis but usually do so in silence, undetected by traditional radar and rankings, often unaware themselves of their high risk for being pushed or pulled into a full crisis.
Ganther, Felicia, Prostollo, Warren, Jackson, Tara, Rhodes, Scott, Knapp, Julie, McGowan, Kelly, Woods, Larry, Norris, Pat, Strong, Ed, Maguire, Rita, Koppell, Jonathan G.S., Kenworthy, Lane, Bjorklund, Eric, Goldsmith, Susan, Snider, David, Fabes, Richard, Zwick, Cynthia, Kittle, Jay, Fidlin, Billie, Harper-Marinick, Maria, Colton, Arlan, Hengehold, Kevin, Pedigo, Steve, McWhortor, Patrick, Demarchi, Kim, Dobras, Darryl, McNamee, Elizabeth, Theisen, Marissa, Newton, Ray, de la Cruz-Parra, Luis, Wogan, Terri, Shafer, Michael S., Perales, Kathleen, Banks, Andrea, Sampson, Chad, Garcia, Joseph, Rosenfed, Fred, Babich, Nina, Holoway, Jim, Adams-Clement, Antonia, Smith, Julia Grace, Wastchak, Devan, Strain, Bob, Pfister, Suzanne, Black, Luke, Ostos, Ray   +45 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

The Impact of Kefir Consumption on Inflammation, Oxidative Stress Status, and Metabolic-Syndrome-Related Parameters in Animal Models: A Systematic Review and Meta-Analysis

Foods
Metabolic syndrome (MetS) is a complex condition defined by central obesity, insulin resistance, dyslipidemia, and systemic inflammation. Kefir, a fermented beverage rich in probiotics and beneficial compounds, has emerged as a functional food that may ...
Zahid Naeem Qaisrani, Wai Phyo Lin, Bo Bo Lay, Khin Yadanar Phyo, Myat Mon San, Nurulhusna Awaeloh, Sasithon Aunsorn, Rinrada Pattanayaiying, Susakul Palakawong Na Ayudthaya, Choosit Hongkulsup, Nirunya Buntin, Sasitorn Chusri   +11 more
doaj   +1 more source

Mobilizing for a war on the home front against sugar-related morbidity and mortality

Israel Journal of Health Policy Research, 2017
In Israel today, there are 420,200 Israelis diagnosed with diabetes, and every year, Israelis sustain thousands of diabetes-related deaths and tens of thousands of diabetes-related amputations.
Dean Schillinger, James G. Kahn
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

CKD Awareness in the General Population: Performance of CKD-Specific Questions

Kidney Medicine, 2019
Rationale & Objective: Data from patients in one delivery system have suggested that the prevalence of chronic kidney disease (CKD) awareness differs by how the question is asked.
Delphine S. Tuot, Karen K. Wong, Alexandra Velasquez, Deidra C. Crews, Alan B. Zonderman, Michele K. Evans, Neil R. Powe   +6 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source