Results 81 to 90 of about 8,761,625 (347)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Special Issue- Engaging Vulnerable Populations in the Co-Production of Public Services

, 2021
Increasing recognition of the expertise derived from lived experience and the potential value of involving service users as partners in the governance and provision of public services has led to renewed international interest in the co-production of such
G. Mulvale, G. Robert
semanticscholar   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Clinical Potential of Curcuma longa Linn. as Nutraceutical/Dietary Supplement for Metabolic Syndrome: Systematic Review and Meta-Analysis of Randomized Controlled Trials

Foods
Metabolic syndrome (MetS) and its associated conditions, namely, type 2 diabetes mellitus (T2DM), non-alcoholic fatty liver disease (NAFLD), obesity, and polycystic ovary syndrome (PCOS) are characterized by insulin resistance, dyslipidemia, and low ...
Samuel Abiodun Kehinde, Zahid Naeem Qaisrani, Rinrada Pattanayaiying, Bo Bo Lay, Khin Yadanar Phyo, Wai Phyo Lin, Myat Mon San, Nurulhusna Awaeloh, Sasithon Aunsorn, Ran Kitkangplu, Sasitorn Chusri   +10 more
doaj   +1 more source

An electronic registry to improve adherence to active surveillance monitoring among men with prostate cancer at a safety-net hospital: protocol for a pilot study

Pilot and Feasibility Studies, 2019
Background The evidence-based practice of active surveillance to monitor men with favorable-risk prostate cancer in lieu of initial definitive treatment is becoming more common. However, there are barriers to effective implementation, particularly in low-
Benjamin Cedars, Sarah Lisker, Hala T. Borno, Puneet Kamal, Benjamin Breyer, Urmimala Sarkar   +5 more
doaj   +1 more source

Religion, spirituality and diurnal rhythms of salivary cortisol and dehydroepiandrosterone in postmenopausal women

Comprehensive Psychoneuroendocrinology, 2021
Background: Religion and spirituality (R/S) are important resources for coping with stress and are hypothesized to influence health outcomes via modulation of the hypothalamic-pituitary-adrenal (HPA) axis, though this has not been evaluated extensively ...
Oluwaseyi O. Isehunwa, Erica T. Warner, Donna Spiegelman, Tianyi Huang, Shelley S. Tworoger, Blake Victor Kent, Alexandra E. Shields   +6 more
doaj   +1 more source

Children as a Vulnerable Population

Human and Ecological Risk Assessment: An International Journal, 2005
Children are not little adults. They have unique patterns of environmental exposure and developmentally determined susceptibilities that increase their risk of disease following toxic environmental exposure. Evidence is accumulating that children's exposure to toxic chemicals in the environment is contributing to changing patterns of pediatric disease.
openaire   +2 more sources

Rising Poverty in the Midst of Plenty: The Case of Working-Age People with Disabilities over the Business Cycles of the 1980s and 1990s. Policy Brief [PDF]

, 2005
“When you cannot measure, your knowledge is meager and unsatisfactory”—Lord Kelvin. (Chiseled on the archway of the University of Chicago Social Sciences Building).
Burkhauser, Richard V., Houtenville, Andrew J., Rovba , Ludmila   +2 more
core   +2 more sources

Ethical considerations and challenges for using digital ethnography to research vulnerable populations

Journal of business research, 2020
The social technologies of the web permit new techniques of research to emerge, often with novel ethical challenges. One such technique is digital ethnography. While there is a robust literature associated with digital approaches to ethnography, there is
Alexander Thompson, L. Stringfellow, M. Maclean, Amal Nazzal   +3 more
semanticscholar   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source