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From cervix to multisite: Detection of lower genital tract lesions in a 10-year cross-sectional colposcopy clinic study. [PDF]
PLoS OneYan Z +12 more
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Vulvar intraepithelial neoplasia
Best Practice and Research in Clinical Obstetrics and Gynaecology, 2014Vulvar intraepithelial neoplasia (VIN) is a high-grade intraepithelial squamous lesion and precursor of invasive squamous cell carcinoma (SCC). The 2004 International Society for the Study of Vulvovaginal Disease (ISSVD) classification distinguished two types of VIN: usual type (human papillomavirus (HPV)-related) and differentiated type (not HPV ...
Leonardo Micheletti, Mario Preti
exaly +5 more sources
Women's Experiences With Vulvar Intraepithelial Neoplasia
JOGNN - Journal of Obstetric, Gynecologic, and Neonatal Nursing, 2008To explore women's experiences with vulvar intraepithelial neoplasia during diagnosis and treatment.Two focus groups, each with 3 participants, were conducted as a pilot study. Participants were asked open-ended questions about their experiences, quality of life, sexual functioning, body image, and well-being.
exaly +3 more sources
Treatment of Vulvar Intraepithelial Neoplasia with Topical Imiquimod
New England Journal of Medicine, 2008Alternatives to surgery are needed for the treatment of vulvar intraepithelial neoplasia. We investigated the effectiveness of imiquimod 5% cream, a topical immune-response modulator, for the treatment of this condition.Fifty-two patients with grade 2 or 3 vulvar intraepithelial neoplasia were randomly assigned to receive either imiquimod or placebo ...
Manon van Seters +2 more
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Vulvar intraepithelial neoplasia: Risk factors for recurrence
Gynecologic Oncology, 2018We studied a large population of women with high-grade vulvar intraepithelial neoplasia (VIN) in order to identify patient and treatment-related risk factors for recurrence and progression to cancer.For this retrospective cohort study of women with a histologic diagnosis of VIN within Southern California Permanente Medical Group between 1995 and 2007 ...
C H Holschneider
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Angiogenesis in Vulvar Intraepithelial Neoplasia
Gynecologic Oncology, 1997Vulvar intraepithelial neoplasia (VIN) has been reported to be a precursor of invasive vulvar cancer. Switching to the angiogenic phenotype is considered a key step in tumor growth. Microvessel density (MVD) and vascular endothelial growth factor (VEGF), a highly angiogenic peptide, are important parameters of tumor angiogenesis. Forty-three histologic
Banchertodesca, D +7 more
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Vulvar intraepithelial neoplasia and carcinoma
Seminars in Cutaneous Medicine and Surgery, 1998This report describes the classification, clinical profile, etiology, and management of high-grade squamous vulvar intraepithelial-neoplasia (VIN). Recent studies have better defined the progressive potential of high-grade VIN and the relationship of such lesions to squamous vulvar carcinoma.
M J, Campion, N F, Hacker
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