Results 1 to 10 of about 234,309 (195)

Vulvar squamous intraepithelial neoplasia epithelial thickness in hairy and non-hairy sites: a single center experience from China. [PDF]

Front Oncol, 2023
IntroductionA large-sample study focusing on VIN lesions of a more precise thickness is needed to help guide clinical treatment. This study aimed to investigate the depth of vulvar intraepithelial neoplasia (VIN) and involved skin appendages to provide ...
Xiao J, Chen Z, Xiao Y, Sui L, Wang C, Cong Q.   +5 more
europepmc   +4 more sources

The Role of Photodynamic Therapy in the Treatment of Vulvar Intraepithelial Neoplasia [PDF]

Biomedicines, 2018
Background: vulvar intraepithelial neoplasia is a non-invasive precursor lesion found in 50–70% of patients affected by vulvar squamous cell carcinoma. In the past, radical surgery was the standard treatment for vulvar intraepithelial neoplasia, however,
Anna Daniela Iacobone, Giulio Tosti, Eleonora Petra Preti   +2 more
exaly   +4 more sources

Extended High-Risk HPV Genotyping With BD Onclarity Enhances Anal Cancer Screening Among High-Risk Populations: A Cross-Sectional Study. [PDF]

Diagn Cytopathol
ABSTRACT Background Anal cancer rates are rising among women, immunocompromised individuals, and Men who have sex with Men (MSM), independent of HIV status. While high‐resolution anoscopy remains the diagnostic standard, limited access has increased interest in alternative screening.
Maharjan D, Waters J, Randolph M, Shuler B, Borum J, Segura S.   +5 more
europepmc   +2 more sources

Large Anogenital Bowen Disease Misdiagnosed as Chronic Eczema for Nine Years: A Case Report Highlighting the Importance of Early Biopsy. [PDF]

Clin Case Rep
ABSTRACT Persistent treatment‐resistant anogenital plaques should not be repeatedly managed as chronic eczema without histopathological confirmation. Early biopsy of atypical or non‐resolving lesions facilitates timely diagnosis of Bowen disease, prevents prolonged diagnostic delay, and enables treatment before progression to invasive squamous cell ...
Acharya SS, Bishokarma S, Giri U.
europepmc   +2 more sources

Risk stratification and anal cancer screening in immunocompetent women with genital HPV: Value of multicentric HSIL and performance of HPV-based screening. [PDF]

Int J Cancer
What's new? Anal squamous cell carcinoma (ASCC) incidence is increasing, with most cases occurring in immunocompetent women. ASCC risk is linked in particular to genital human papillomavirus (HPV) infection and HPV‐associated high‐grade squamous intraepithelial lesions (HSILs).
Matas I, Torné A, Saco A, Martí C, Cardiel A, Rakislova N, Marimon L, Glickman A, Victoria I, Alós S, Lopez-Diaz J, Fusté P, Ordi J, Del Pino M.   +13 more
europepmc   +2 more sources

Stratifying the risk of anal high-grade squamous intraepithelial lesion among immunosuppressed women with genital HPV. [PDF]

Front Immunol
IntroductionImmunosuppressed women with human papillomavirus (HPV)-related genital disease are at increased risk of anal squamous cell carcinoma (ASCC), yet optimal risk stratification and screening strategies remain poorly defined. The aim of this study
Matas I, Pifarré M, Torné A, Saco A, Darecka K, Guerra E, Martí C, Bruch J, Cardiel A, Rakislova N, Marimon L, Mayordomo-Bofill I, Victoria I, Alós S, Fusté P, Ordi J, Del Pino M.   +16 more
europepmc   +2 more sources

The Varying Faces of Vulvar Neoplasia. [PDF]

Indian Dermatol Online J
Vulvar neoplasia is on the rise and patients often present to dermatologists with lesions of varying morphology associated with pruritus, burning sensation, or pain.
Athota K, Prabhu SS, Gopinathan N.
europepmc   +2 more sources

Aggressive squamous cell carcinomas arising from mucosal lichen planus: A report of three cases. [PDF]

J Dtsch Dermatol Ges
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 8, Page e1129-e1132, August 2026.
Cramer N, Wilsmann-Theis D, Schön MP, Wenzel J, Gallwas J, Mössner R.   +5 more
europepmc   +2 more sources

HPV-independent vulvar squamous cell carcinoma: a case report and review of the literature. [PDF]

Einstein (Sao Paulo)
Vulvar cancer, a rare gynecological malignancy, accounts for 3-5% of cases and is most commonly squamous cell carcinoma. Prognosis is poorer in cancers unrelated to human papillomavirus (HPV), often associated with chronic inflammation.
Haddad RF, Wyper MHB, Esperança SD, Callado GY, Prigenzi KCK, Tso FK, Belfort-Mattos PN.   +6 more
europepmc   +3 more sources

Active surveillance of cervical intraepithelial neoplasia and adverse pregnancy outcomes: A register-based cohort study. [PDF]

Acta Obstet Gynecol Scand
Active surveillance for cervical intraepithelial neoplasia grade 2 is not associated with increased risks of adverse pregnancy outcomes compared to large loop excision of the transformation zone. Abstract Introduction Previous studies have suggested that human papillomavirus (HPV) and HPV‐related disease may be associated with increased risk of adverse
Katholm KK, Eriksen LK, Lycke KD, Larsen NL, Sundtoft I, Randrup TH, Hammer A.   +6 more
europepmc   +2 more sources