Results 131 to 140 of about 61,670 (295)

Clusterin knockdown has effects on intracellular and secreted von Willebrand factor in human umbilical vein endothelial cells.

PLoS ONE
Alterations in von Willebrand factor (VWF) have an important role in human health and disease. Deficiency of VWF is associated with symptoms of bleeding and excesses of VWF are associated with thrombotic outcomes.
Allaura A Cox, Alice Liu, Christopher J Ng   +2 more
doaj   +1 more source

Inhibition of the von Willebrand (VWF)-collagen interaction by an antihuman VWF monoclonal antibody results in abolition of in vivo arterial platelet thrombus formation in baboons

, 2002
The interaction between collagen, von Willebrand factor (VWF), and glycoprotein Ib is the first step in hemostasis and thrombosis especially under high shear conditions.
Depraetere, Hilde, Cauwenberghs, Nancy, Meiring, Muriel, Wu, Dongmei, Vanhoorelbeke, Karen, Deckmyn, Hans, Kotze, Harry F.   +6 more
core   +1 more source

Surface charge alterations in urinary extracellular vesicles mirror diabetic kidney disease pathophysiology

The FEBS Journal, EarlyView.
This study reveals that changes in the electrical charge, that is zeta potential of large extracellular vesicles (uEVs) found in urine, can reflect disease progression from diabetes to kidney scarring (fibrosis). With further clinical development, measurement of uEVs charge could provide a simple, noninvasive way to monitor disease progression and help
Melanie Tepuš, Maria Pia Savoca, Mabrouka Maamra, Conor J. Meehan, Dimitrios S. Goumenos, Timothy Johnson, Elisabetta A. M. Verderio   +6 more
wiley   +1 more source

Management of COVID-19 associated coagulopathy in critically ill patients and the risk of acquired von willebrand syndrome

Scientific Reports
This study investigated the interplay between thrombosis and hemorrhage in critically ill COVID-19 patients, particularly those on extracorporeal membrane oxygenation (ECMO).
Hiroyasu Ishikura, Yuhei Irie, Maiko Nakashio, Junichi Maruyama, Yoshihiko Nakamura, Takahiro Yamagaito, Maho Yoshida, Hiroki Hatomoto, Shintaro Yamasaki, Kota Hoshino   +9 more
doaj   +1 more source

Stul polymorphisms in the vWF gene [PDF]

Nucleic Acids Research, 1990
A, Inbal, R I, Handin
openaire   +2 more sources

vWF sequences

, 2016
Nexus file containing phased alleles from vWF sequences of Sunda shelf Crocidura.
Handika, Heru, Demos, Terrence C., Thomas C. Giarla (3199704), Maharadatunkamsi (3199695), Heru Handika (3199701), Kevin C. Rowe (223136), Terrence C. Demos (798528), Jacob A. Esselstyn (214666), Rowe, Kevin C., Anang S. Achmadi (3199698), Giarla, Thomas C., Esselstyn, Jacob A., Maharadatunkamsi, Achmadi, Anang S.   +13 more
core   +1 more source

Contrasting Approaches in the Implementation of GRADE Methodology in Guidelines for Haemophilia and Von Willebrand Disease

Haemophilia, EarlyView.
ABSTRACT Introduction The 2024 ISTH clinical practice guideline (CPG) for treatment of congenital haemophilia, the NBDF‐McMaster Guideline on Care Models for Haemophilia Management, and ASH ISTH NBDF WFH guidelines on the diagnosis and management of VWD all utilised GRADE methodology.
Mark W. Skinner, Manuela Albisetti, Jesús Ardila, Jan Astermark, Jan Blatny, Manuel Carcao, Pratima Chowdary, Nathan T. Connell, Miguel Crato, Yesim Dargaud, Roseline d'Oiron, Amy L. Dunn, Miguel A. Escobar, Carmen Escuriola‐Ettingshausen, Emna Gouider, Annie Harroche, Cedric Hermans, Victor Jimenez‐Yuste, Radoslaw Kaczmarek, Gili Kenet, Liane Khoo, Robert Klamroth, Florian Langer, David Lillicrap, Johnny Mahlangu, Christoph Male, Tadashi Matsushita, Sandrine Meunier, Wolfgang Miesbach, Beatrice Nolan, Johannes Oldenburg, Brian O'Mahony, Margareth Ozelo, Glenn F. Pierce, Gloria Ramos, Michael Recht, Olivia Romero‐Lux, Dawn Rotellini, Rita C. Santoro, Tammuella C. Singleton, Alok Srivastava, Sophie Susen, Kate Talks, Huyen Tran, Leonard A. Valentino, Jerzy Windyga, Renchi Yang, Maria Elisa Mancuso, also on behalf of AICE, AHAD‐AP, AHCDC, ATHN, CLAHT, EHC, French CRH & MHEMO, HTCCNC, NBDF, PEDNET, UKHCDO, WFH   +59 more
wiley   +1 more source

Recent advances in the diagnosis of von Willebrand disease

LabMed Discovery
Von Willebrand disease (VWD) is caused by a quantitative or qualitative defect of von Willebrand factor (VWF). Despite its prevalence as the most common hereditary bleeding disorder and the associated morbidity, its diagnosis and classification remains a
Qian Liang, Renhao Li
doaj   +1 more source

HETEROGENEITY OF ANTI-VON WILLEBRAND FACTOR (VWF) ANTIBODIES WHICH INHIBIT RISTOCETIN-INDUCED VWF BINDING TO PLATELET GLYCOPROTEIN (GP)Ⅰb [PDF]

, 1989
The epitopes of four anti-vWF monoclonal antibodies (MoAbs), which inhibit antibiotic ristocetin induced vWF binding to GPⅠb, were investigated and compared with each other.
高瀬, 俊夫, 吉岡, 章, 西尾, 健治, 藤村, 吉博, 中井, 寛明, 新家, 興, 金田, 美喜夫, 福井, 弘, 嶋, 緑倫   +8 more
core  

Alternative allele/indel frequencies in mutated positions collected from gene-specific databases, http://www.factorviii-db.org, http://www.factorix.org and https://grenada.lumc.nl/LOVD2/VWF/home.php?select_db=VWF.

, 2019
Alternative allele/indel frequencies in mutated positions collected from gene-specific databases, http://www.factorviii-db.org, http://www.factorix.org and https://grenada.lumc.nl/LOVD2/VWF/home.php?select_db=VWF.
Rolf Ljung (6640649), Jan Astermark (6640652), Christina Lind-Halldén (3163089), Eric Manderstedt (4814349), Rosanna Nilsson (6640646), Christer Halldén (224663)   +5 more
core   +1 more source