ADAMTS-1, ADAMTS-5 and ADAMTS-13 are considered potential targets in the treatment of frozen shoulder [PDF]
Journal of Orthopaedic Surgery and ResearchBackground Frozen shoulder (FS) is a condition that causes shoulder pain and restricted movement, primarily due to inflammation, fibrosis, and adhesion of the shoulder joint capsule. It commonly affects individuals aged 30 to 60 years.
Zihao Zhou, Guanhong Chen
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The Prognostic Value of ADAMTS-13 and von Willebrand Factor in COVID-19 Patients: Prospective Evaluation by Care Setting [PDF]
Diagnostics, 2021 Background: Endothelial dysfunction, coupled with inflammation, induces thrombo-inflammation. In COVID-19, this process is believed to be associated with clinical severity.
Giovanni Tiscia +11 more
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Immune thrombotic thrombocytopenic purpura: Personalized therapy using ADAMTS‐13 activity and autoantibodies [PDF]
Research and Practice in Thrombosis and Haemostasis, 2021 Recently, treatment of immune‐mediated thrombotic thrombocytopenic purpura (ITTP) has changed with the advent of caplacizumab in clinical practice.
Francesca Palandri +8 more
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Economic impact of a rapid, on‐demand ADAMTS‐13 activity assay for the diagnosis of thrombotic thrombocytopenic purpura [PDF]
Research and Practice in Thrombosis and Haemostasis, 2022 Background Thrombotic thrombocytopenic purpura (TTP) is a rare, life‐threatening thrombotic microangiopathy (TMA), characterized by ADAMTS‐13 activity
Alicia White +4 more
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A comparative study of anti–ADAMTS-13 antibody dynamics in immune-mediated thrombotic thrombocytopenic purpura [PDF]
Research and Practice in Thrombosis and HaemostasisBackground: Thrombotic thrombocytopenic purpura, particularly its immune-mediated variant (iTTP), necessitates accurate diagnostic approaches for effective management.
Maria Rita Cozzi +3 more
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ADAMTS-13 and HMGB1-induced oxidative stress in Taenia multiceps-infected animals [PDF]
Scientific Reports, 2023 This study investigated the cytotoxic effects of oxidative stress (OS), high mobility group box 1 (HMGB1), ADAMTS (A disintegrin and metalloproteinase with thrombospondin motifs), and neuropathology associated with coenurus cerebralis (Taenia multiceps).
Gungor Cagdas Dincel +4 more
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Relationship Between Intraluminal Thrombus Volume and Circulating ADAMTS-13 Activity in Abdominal Aortic Aneurysms [PDF]
EJVES Vascular ForumIntroduction: Abdominal aortic aneurysms (AAAs) with intraluminal thrombus (ILT) are suggested to be more prone to rupture than AAAs without. Prior studies indicate that the von Willebrand factor (vWf) plays a role in the formation of ILT since a ...
Qasam M. Ghulam +3 more
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Monitoring ADAMTS-13 conformation in immune-mediated thrombotic thrombocytopenic purpura: toward personalized management [PDF]
Research and Practice in Thrombosis and HaemostasisBackground: Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is a life-threatening thrombotic microangiopathy caused by an autoimmune-driven deficiency of ADAMTS-13.
Bérangère S. Joly +5 more
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ADAMTS-13 activity in stroke of known and unknown cause: Relation to vascular risk factor burden [PDF]
Frontiers in Neurology, 2023 BackgroundThe identification of the underlying mechanism in ischemic stroke has important implications for secondary prevention. A disintegrin and metalloprotease with a thrombospondin type 1 motif, member 13 (ADAMTS-13) has antithrombotic properties and
Gerrit M. Grosse +14 more
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Low ADAMTS‐13 predicts adverse outcomes in hospitalized patients with suspected heparin‐induced thrombocytopenia [PDF]
Research and Practice in Thrombosis and Haemostasis, 2021 Background Heparin‐induced thrombocytopenia (HIT) is a life‐threatening thrombotic complication after heparin exposure. However, the role of ADAMTS‐13 and von Willebrand factor (VWF) in the disease process and outcomes of HIT is not known.
Meng Chan, Xinyang Zhao, X. Long Zheng
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