ADAMTS-13 gene expression in antiphospholipid syndrome [PDF]
Turkish Journal of Hematology, 2011 OBJECTIVE: Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by recurrent thrombosis and fetal mortality. Thrombotic microangiopathy (TMA) is an important histological finding in catastrophic APS (CAPS) and in APS patients with ...
Veysel Sabri Hançer +2 more
doaj +6 more sources
Thrombotic thrombocytopenic purpura with decreased level of ADAMTS-13 activity and increased level of ADAMTS-13 inhibitor in an adolescent [PDF]
Korean Journal of Pediatrics, 2010 Thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathy characterized by endothelial cell damage, resulting in microangiopathic hemolytic anemia, thrombocytopenia, and various degrees of neurological and renal impairment caused by ...
Eun Mi Yang +6 more
doaj +3 more sources
Plasma Levels of ADAMTS-13 Antigen, ADAMTS-13 Inhibitor, ADAMTS-13 Activity, and Von Willebrand Factor in Patients with Behçet's Disease. [PDF]
Mediterr J RheumatolBackground: Beh ; ccedil;et's Disease (BD) is characterised by recurrent aphthous oral and genital ulcers. Vascular involvement is one of the poor prognostic factors.
Karasu U +8 more
europepmc +4 more sources
ADAMTS-13 and bleeding phenotype in von Willebrand disease. [PDF]
Res Pract Thromb Haemost, 2020 Background: The bleeding phenotype of von Willebrand disease (VWD) varies highly between patients and can only partly be explained by von Willebrand factor (VWF) parameters.
Boender J +13 more
europepmc +15 more sources
Prognostic value of von Willebrand factor and ADAMTS-13 in patients with sepsis-induced coagulopathy [PDF]
Research and Practice in Thrombosis and HaemostasisBackground: The von Willebrand factor (VWF)– a disintegrin and metalloprotease with thrombospondin type 1 repeats, member 13 (ADAMTS-13) axis may contribute to microvascular thrombosis and poor outcomes in sepsis-induced coagulopathy (SIC).
Feng Zhang +3 more
doaj +2 more sources
ADAMTS-1, ADAMTS-5 and ADAMTS-13 are considered potential targets in the treatment of frozen shoulder [PDF]
Journal of Orthopaedic Surgery and ResearchBackground Frozen shoulder (FS) is a condition that causes shoulder pain and restricted movement, primarily due to inflammation, fibrosis, and adhesion of the shoulder joint capsule. It commonly affects individuals aged 30 to 60 years.
Zihao Zhou, Guanhong Chen
doaj +2 more sources
The Prognostic Value of ADAMTS-13 and von Willebrand Factor in COVID-19 Patients: Prospective Evaluation by Care Setting [PDF]
Diagnostics, 2021 Background: Endothelial dysfunction, coupled with inflammation, induces thrombo-inflammation. In COVID-19, this process is believed to be associated with clinical severity.
Giovanni Tiscia +11 more
doaj +2 more sources
Immune thrombotic thrombocytopenic purpura: Personalized therapy using ADAMTS‐13 activity and autoantibodies [PDF]
Research and Practice in Thrombosis and Haemostasis, 2021 Recently, treatment of immune‐mediated thrombotic thrombocytopenic purpura (ITTP) has changed with the advent of caplacizumab in clinical practice.
Francesca Palandri +8 more
doaj +2 more sources
Further characterization of ADAMTS-13 inactivation by thrombin [PDF]
Journal of Thrombosis and Haemostasis, 2007 Background: The multimeric size and platelet-tethering function of von Willebrand factor (VWF) are modulated by the plasma metalloprotease, a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS-13).
Lane, DA +4 more
core +5 more sources
Economic impact of a rapid, on‐demand ADAMTS‐13 activity assay for the diagnosis of thrombotic thrombocytopenic purpura [PDF]
Research and Practice in Thrombosis and Haemostasis, 2022 Background Thrombotic thrombocytopenic purpura (TTP) is a rare, life‐threatening thrombotic microangiopathy (TMA), characterized by ADAMTS‐13 activity
Alicia White +4 more
doaj +2 more sources