Results 1 to 10 of about 4,617,323 (138)

Clinical relapse of immune‐mediated thrombotic thrombocytopenic purpura following COVID‐19 vaccination

Research and Practice in Thrombosis and Haemostasis, 2022
De novo and relapsed immune‐mediated thrombotic thrombocytopenic purpura (iTTP) have been documented to have occurred following severe acute respiratory syndrome coronavirus 2 (COVID‐19) vaccination.
William Deucher, Senthil Sukumar, Spero R. Cataland   +2 more
doaj   +1 more source

Von Willebrand factor cleaving protease (ADAMTS-13) in 123 patients with connective tissue diseases (systemic lupus erythematosus and systemic sclerosis)

Haematologica, 2003
BACKGROUND AND OBJECTIVES: Autoantibodies inactivating the von Willebrand factor (VWF) cleaving protease, ADAMTS-13, are among the most frequent causes of thrombotic thrombocytopenic purpura (TTP).
PM Mannucci, M Vanoli, I Forza, MT Canciani, R Scorza   +4 more
doaj  

ADAMTS 1, 4, 12, and 13 levels in maternal blood, cord blood, and placenta in preeclampsia

Hypertension in Pregnancy, 2018
The aim of this study is to compare ADAMTS (A Disintegrin and Metalloprotease Domains with Thrombospondins motifs) 1, 4, 12, and 13 levels in maternal and cord blood and placental tissue between preeclampsia and uncomplicated pregnancies.
Müberra Namlı Kalem, Ziya Kalem, Tuncay Yüce, Feride Soylemez   +3 more
doaj   +1 more source

ADAMTS-13 in the Diagnosis and Management of Thrombotic Microangiopathies

Rambam Maimonides Medical Journal, 2014
Thrombotic microangiopathies (TMAs) comprise a group of distinct disorders characterized by microangiopathic hemolytic anemia, thrombocytopenia, and microvascular thrombosis.
Galit Sarig
doaj   +1 more source

ADAMTS-3, -13, -16, and -19 levels in patients with habitual abortion

Kaohsiung Journal of Medical Sciences, 2017
A disintegrin-like and metalloproteinase domain with thrombospondin-type 1 motifs (ADAMTS) protein superfamily includes 19 secreted metalloproteases. Proteolytic substrates of ADAMTS enzymes have been linked to reproductive function.
Meryem Kuru Pekcan, Esma Sarıkaya, Aytekin Tokmak, Murat Alışık, Afra Alkan, Gülnur Özakşit, Özcan Erel   +6 more
doaj   +1 more source

Serum ADAMTS-13 Levels as an Indicator of Portal Vein Thrombosis

Gastroenterology Research and Practice, 2018
Background. Coagulation disorders in patients with liver cirrhosis are a common clinical problem. Cirrhosis should be considered a state of impaired blood clotting or an imbalance of the whole coagulation system.
Tomasz Mikuła, Joanna Kozłowska, Wojciech Stańczak, Mariusz Sapuła, Aleksandra Różyk, Alicja Wiercińska-Drapało   +5 more
doaj   +1 more source

Prognostic role of the vWF/ADAMTS-13 axis in thrombosis risk stratification in gynecologic oncology patients

Акушерство, гинекология и репродукция
Aim: to evaluate a prognostic significance for the vWF/ADAMTS-13 (von Willebrand factor/a disintegrin and metalloprotease with thrombospondin type 1 motif, member 13) ratio as an integral biomarker for stratifying the risk of venous thromboembolic events
A. V. Vorobev, V. O. Bitsadze, A. G. Solopova, J. Kh. Khizroeva, D. O. Utkin, D. О. Ostrikov, D. V. Blinov, J.-C. Gris, I. Elalamy, G. Gerotziafas, A. D. Makatsariya   +10 more
doaj   +1 more source

Splenectomy in relapsing and plasma-refractory acquired thrombotic thrombocytopenic purpura

Haematologica, 2004
BACKGROUND AND OBJECTIVES: Acquired thrombotic thrombocytopenic purpura (TTP) is often due to autoantibodies inhibiting ADAMTS-13 activity resulting in impaired processing of very large von Willebrand factor multimers.
JA Kremer Hovinga, JD Studt, F Demarmels Biasiutti, M Solenthaler, L Alberio, C Zwicky, S Fontana, BM Taleghani, A Tobler, B Laemmle   +9 more
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血浆ADAMTS-13活性和NLR在急性肺血栓栓塞症中的诊断价值

Zhongshan Daxue xuebao. Yixue kexue ban, 2021
目的探究急性肺血栓栓塞症（PTE）患者血浆血管性血友病因子（vWF）活性、血管性血友病因子裂解酶（ADAMTS-13）活性、中性粒细胞计数与淋巴细胞计数比率（NLR）健康对照组的表达差异，探究ADAMTS-13活性、NLR对于PTE患者的诊断意义。方法共纳入急性PTE患者64例及健康对照者30例，收集相关临床数据并采用酶联免疫吸附试验（ELISA）检测血浆ADAMTS-13活性、vWF活性，分析比较ADAMTS-13活性、vWF活性的组间差异及其与其他临床指标的相关性，绘制受试者工作特征曲线（ROC ...
胡子旋, 何婉媚, 曾勉
doaj  

Severe ADAMTS-13 deficiency without hemolysis as a cause of cryptogenic stroke: A single center case series

Journal of Stroke and Cerebrovascular Diseases
Introduction: Cerebral Infarction due to Severe ADAMTS-13 Deficiency (CISAD) remains an underrecognized cause of cryptogenic stroke. Despite the absence of classic hematologic features, CISAD confers a risk of recurrent ischemic events if not promptly ...
Johanna Seiden, MD, MPH, Juan Felipe Daza-Ovalle, MD, Zhengrui Xiao, MD, Olga Rubalsky, MD, Irina Murakhovskaya, MD, Ellen Friedman, MD, Kathryn Kirchoff-Torres, MD, Daniel Labovitz, MD, MS, Charles Esenwa, MD, MS   +8 more
doaj   +1 more source