Prognostic value of von Willebrand factor and ADAMTS-13 in patients with sepsis-induced coagulopathy [PDF]
Research and Practice in Thrombosis and HaemostasisBackground: The von Willebrand factor (VWF)– a disintegrin and metalloprotease with thrombospondin type 1 repeats, member 13 (ADAMTS-13) axis may contribute to microvascular thrombosis and poor outcomes in sepsis-induced coagulopathy (SIC).
Feng Zhang +3 more
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Thrombotic thrombocytopenic purpura with decreased level of ADAMTS-13 activity and increased level of ADAMTS-13 inhibitor in an adolescent [PDF]
Korean Journal of Pediatrics, 2010 Thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathy characterized by endothelial cell damage, resulting in microangiopathic hemolytic anemia, thrombocytopenia, and various degrees of neurological and renal impairment caused by ...
Eun Mi Yang +6 more
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ADAMTS-13 gene expression in antiphospholipid syndrome [PDF]
Turkish Journal of Hematology, 2011 OBJECTIVE: Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by recurrent thrombosis and fetal mortality. Thrombotic microangiopathy (TMA) is an important histological finding in catastrophic APS (CAPS) and in APS patients with ...
Veysel Sabri Hançer +2 more
doaj +4 more sources
ADAMTS-1, ADAMTS-5 and ADAMTS-13 are considered potential targets in the treatment of frozen shoulder [PDF]
Journal of Orthopaedic Surgery and ResearchBackground Frozen shoulder (FS) is a condition that causes shoulder pain and restricted movement, primarily due to inflammation, fibrosis, and adhesion of the shoulder joint capsule. It commonly affects individuals aged 30 to 60 years.
Zihao Zhou, Guanhong Chen
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The Prognostic Value of ADAMTS-13 and von Willebrand Factor in COVID-19 Patients: Prospective Evaluation by Care Setting [PDF]
Diagnostics, 2021 Background: Endothelial dysfunction, coupled with inflammation, induces thrombo-inflammation. In COVID-19, this process is believed to be associated with clinical severity.
Giovanni Tiscia +11 more
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Immune thrombotic thrombocytopenic purpura: Personalized therapy using ADAMTS‐13 activity and autoantibodies [PDF]
Research and Practice in Thrombosis and Haemostasis, 2021 Recently, treatment of immune‐mediated thrombotic thrombocytopenic purpura (ITTP) has changed with the advent of caplacizumab in clinical practice.
Francesca Palandri +8 more
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Economic impact of a rapid, on‐demand ADAMTS‐13 activity assay for the diagnosis of thrombotic thrombocytopenic purpura [PDF]
Research and Practice in Thrombosis and Haemostasis, 2022 Background Thrombotic thrombocytopenic purpura (TTP) is a rare, life‐threatening thrombotic microangiopathy (TMA), characterized by ADAMTS‐13 activity
Alicia White +4 more
doaj +2 more sources
A comparative study of anti–ADAMTS-13 antibody dynamics in immune-mediated thrombotic thrombocytopenic purpura [PDF]
Research and Practice in Thrombosis and HaemostasisBackground: Thrombotic thrombocytopenic purpura, particularly its immune-mediated variant (iTTP), necessitates accurate diagnostic approaches for effective management.
Maria Rita Cozzi +3 more
doaj +2 more sources
ADAMTS-13 and HMGB1-induced oxidative stress in Taenia multiceps-infected animals [PDF]
Scientific Reports, 2023 This study investigated the cytotoxic effects of oxidative stress (OS), high mobility group box 1 (HMGB1), ADAMTS (A disintegrin and metalloproteinase with thrombospondin motifs), and neuropathology associated with coenurus cerebralis (Taenia multiceps).
Gungor Cagdas Dincel +4 more
doaj +2 more sources
Monitoring ADAMTS-13 conformation in immune-mediated thrombotic thrombocytopenic purpura: toward personalized management [PDF]
Research and Practice in Thrombosis and HaemostasisBackground: Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is a life-threatening thrombotic microangiopathy caused by an autoimmune-driven deficiency of ADAMTS-13.
Bérangère S. Joly +5 more
doaj +2 more sources