Results 1 to 10 of about 80,049 (294)

The relationships between disseminated intravascular coagulation and time series change of Von Willebrand factor in patients with out-of-hospital cardiac arrest: a retrospective observational study [PDF]

Thrombosis Journal
Background Out-of-hospital cardiac arrest (OHCA) is frequently complicated by disseminated intravascular coagulation (DIC), which worsens outcomes. Von Willebrand factor (VWF) is central to haemostasis, and its multimeric size and activity are regulated ...
Yuki Itagaki, Yuki Chiba, Misako Suzuki, Mariko Hayamizu, Hisanori Horiuchi, Mineji Hayakawa   +5 more
doaj   +2 more sources

CURRENT KNOWLEDGE ON THE PATHOGENIC MECHANISMS OF HENOCH-SCHOENLEIN PURPURA IN CHILDREN [PDF]

Trakia Journal of Sciences, 2021
The Schӧnlein-Henoch vasculitis is an IgA-mediated inflammation of small vessels. The main clinical manifestation is palpable purpura without thrombocytopenia, manifested by bilateral symmetrical distribution on both lower limbs, abdominal pain, often ...
A.Vasileva, Iv. Chakarov, P. Chakarova
doaj   +1 more source

Prognostic value of von Willebrand factor in clinical practice

Акушерство, гинекология и репродукция, 2022
The von Willebrand factor (vWF) is a multimeric plasma glycoprotein, which quantification has important prognostic value. The current literature review demonstrates a relationship between the disease severity and vWF level.
K. N. Grigoreva, V. O. Bitsadze, J. Kh. Khizroeva, V. I. Tsibizova, M. V. Tretyakova, D. V. Blinov, L. L. Pankratyeva, N. R. Gashimova, F. E. Yakubova, A. S. Antonova, J.-C. Gris, I. Elalamy, A. D. Makatsariya   +12 more
doaj   +1 more source

Immunothrombosis in cancer patients: contribution of neutrophil extracellular traps, ADAMTS-13 and von Willebrand factor

Акушерство, гинекология и репродукция, 2023
Introduction. Neutrophil extracellular traps (NETs) and von Willebrand factor (vWF) are integral players in thrombosis and inflammation in cancer patients. It has been increasingly evident that an active interplay exists between NETs and vWF.
E. V. Slukhanchuk, V. O. Bitsadze, A. G. Solopova, J. Kh. Khizroeva, V. I. Tsibizova, J.-K. Gris, I. Elalamy, D. V. Shcherbakov, L. L. Pankratyeva, L. A. Ashrafyan, A. D. Makatsariya   +10 more
doaj   +1 more source

VWF, Platelets and the Antiphospholipid Syndrome [PDF]

International Journal of Molecular Sciences, 2021
The antiphospholipid syndrome (APS) is characterized by thrombosis and/or pregnancy morbidity with the persistent presence of antiphospholipid antibodies (aPLs). Laboratory criteria for the classification of APS include the detection of lupus anticoagulant (LAC), anti-cardiolipin (aCL) antibodies and anti-β2glycoprotein I (aβ2GPI) antibodies.
Shengshi Huang, Marisa Ninivaggi, Walid Chayoua, Bas de Laat   +3 more
openaire   +3 more sources

Inherited ADAMTS13 mutations associated with Thrombotic Thrombocytopenic Purpura: a short review and update

Platelets, 2023
ADAMTS13 is a plasma metalloprotease with the primary function of cleaving VWF to maintain hemostasis. Circulating ADAMTS13 is in the closed conformation until blood vessel injury triggers a VWF-dependant activation to the open active form of the protein.
Zoe Markham-Lee, Neil V. Morgan, Jonas Emsley   +2 more
doaj   +1 more source

Neonatal thrombosis: risk factors and principles of prophylaxis

Акушерство, гинекология и репродукция, 2021
Data analysis on the pathogenesis and risk factors of neonatal thrombosis was carried out. The main risk factor of any neonatal thrombosis is central catheter installment, but other maternal, fetal and neonatal factors should be taken into consideration.
A. V. Vorobev, V. O. Bitsadze, J. Kh. Khizroeva, S. A. Potapkina, N. A. Makatsariya, G. Rizzo, G. C. Di Renzo, D. V. Blinov, L. L. Pankratyeva, V. I. Tsibizova   +9 more
doaj   +1 more source

Pathogenetic and prognostic significance of inflammation and altered ADAMTS-13/vWF axis in patients with severe COVID-19

Акушерство, гинекология и репродукция, 2022
Introduction. Currently, endothelial dysfunction caused by inflammation and immunothrombosisis considered as one of the crucial mechanisms in developing the SARS-CoV-2 virus-mediated coronavirus disease 2019 (COVID-19). A mass endothelial damage followed
V. O. Bitsadze, J. Kh. Khizroeva, J.-Ch. Gris, S. Schulman, A. S. Shkoda, M. V. Tretyakova, N. A. Makatsariya, E. V. Slukhanchuk, L. L. Pankratyeva, M. I. Petrovskiy, I. V. Mashechkin, D. V. Blinov, V. I. Tsibizova, Z. K. Gadaeva, S. S. Panshin, N. V. Samburova, A. D. Makatsariya   +16 more
doaj   +1 more source

Hemostatic factors and risk of coronary heart disease in general populations: new prospective study and updated meta-analyses [PDF]

, 2013
<p>Background: Activation of blood coagulation and fibrinolysis may be associated with increased risk of coronary heart disease. We aimed to assess associations of circulating tissue plasminogen activator (t-PA) antigen, D-dimer and von Willebrand ...
Aspelund, T., Di Angelantonio, E., Eiriksdottir, G., Gudnason, V., Lowe, G., Rumley, A., Thompson, A., Willeit, P.   +7 more
core   +14 more sources

Clinical significance of assessing ADAMTS-13 and von Willebrand factor level in COVID-19 convalescent pregnant women

Акушерство, гинекология и репродукция, 2023
Introduction. Coronavirus infection is associated with severe endotheliopathy, thromboinflammation and immunothrombosis leading to excessive release of von Willebrand factor (vWF) multimers from Weibel–Palade bodies, which can affect activity of ADAMTS ...
N. R. Gashimova, K. N. Grigoreva, V. O. Bitsadze, L. L. Pankratyeva, J. Kh. Khizroeva, M. V. Tretyakova, Ya. M. Shammut, E. Iu. Iupatov, V. I. Tsibizova, J.-K. Gris, D. V. Blinov, A. D. Makatsariya   +11 more
doaj   +1 more source