Results 31 to 40 of about 56,156 (204)

ADAMTS-13 proteolyzed by thrombin has reduced affinity for von Willebrand factor (VWF) [PDF]

, 2011
(A) 6 n ADAMTS-13, 60 n thrombin-cleaved ADAMTS-13 (ADAMTS-13/FIIa) or 60 n thrombin-cleaved ADAMTS-13/6 n ADAMTS-13 (10:1 mix) was incubated with 10 n purified plasma-derived VWF in the presence of 1.5 urea and 5 m BaCl.
C K N K CHION (48919), S ZANARDELLI (48920), J T B CRAWLEY (48922), J K LAM (48918), D A LANE (48921)   +4 more
core   +1 more source

Levels of von Willebrand factor antigen and von Willebrand factor cleaving protease (ADAMTS13) activity predict clinical events in chronic heart failure. [PDF]

, 2009
Decreased activity of ADAMTS13, the von Willebrand factor (VWF) cleaving protease, was recently reported in cardiovascular diseases and in hepatic failure.
Borgulya, Gábor, Hársfalvi, Jolán, Gombos, Tímea, Cervenak, László, Jánoskuti, Lívia, Förhécz, Zsolt, Prohászka, Zoltán, Papassotiriou, Jana, Makó, Veronika, Pozsonyi, Zoltán, Kunde, Jan   +10 more
core   +1 more source

Neutrophil extracellular traps: a role in inflammation and dysregulated hemostasis as well as in patients with COVID-19 and severe obstetric pathology

Акушерство, гинекология и репродукция, 2021
Numerous studies have proven a close relationship between inflammatory diseases and the state of hypercoagulability. In fact, thromboembolic complications represent one of the main causes of disability and mortality in acute and chronic inflammatory ...
A. D. Makatsariya, E. V. Slukhanchuk, V. O. Bitsadze, J. Kh. Khizroeva, M. V. Tretyakova, N. A. Makatsariya, S. V. Akinshina, A. S. Shkoda, L. L. Pankratyeva, G. C. Di Renzo, G. Rizzo, K. N. Grigorieva, V. I. Tsibizova, J.-C. Gris, I. Elalamy   +14 more
doaj   +1 more source

Increased plasma von Willebrand factor antigen levels but normal von Willebrand factor cleaving protease (ADAMTS13) activity in preeclampsia. [PDF]

, 2009
The activity of ADAMTS13, the von Willebrand factor (VWF) cleaving protease is low in several conditions, including HELLP (haemolysis, elevated liver enzymes, and low platelet count) syndrome.
Hársfalvi, Jolán, Molvarec, Attila, Gombos, Tímea, Udvardy, Miklós László, Cervenak, László, Derzsy, Zoltán, Prohászka, Zoltán, Rigó, János, Bõze, Tamás, Makó, Veronika   +9 more
core   +1 more source

VWF clearance: it’s glycomplicated [PDF]

Blood, 2018
In this issue of Blood , Ward et al demonstrate that a loss of sialic acids turns von Willebrand factor (VWF) into a ligand for the scavenger-receptor macrophage galactose-type lectin (MGL ...
Denis, Cécile, Lenting, Peter
openaire   +2 more sources

GrM cleaves VWF. [PDF]

, 2013
(A) Purified plasma VWF (5 µg/mL) was incubated with various purified recombinant granzymes (300 nM) in TBS for 1 hour at 37°C and analyzed by immuno blot, using an antibody against VWF.
Martine J. Hollestelle (345019), Philip G. de Groot (167182), Tom Sprong (278692), Peter J. Lenting (133252), Niels Bovenschen (345021), Ka Wai Lai (345020), Marcel van Deuren (15650)   +6 more
core   +1 more source

The Level of vWF Antigen and Coagulation Markers in Hospitalized Patients with Covid-19

Journal of Blood Medicine, 2021
Hadeel Al Otair,1 Khalid AlSaleh,2 Fatmah S AlQahtany,3 Khalid Al Ayed,1 Hessah Al Ammar,4 Noura Al Mefgai,4 Faisal Al Zeer5 1Department of Medicine, King Saud University Medical city (KSUMC), King Saud University, Riyadh, Saudi Arabia; 2Department of ...
Al Otair H, AlSaleh K, AlQahtany FS, Al Ayed K, Al Ammar H, Al Mefgai N, Al Zeer F   +6 more
doaj  

Utility of microfluidic devices to study the platelet–endothelium interface

Platelets, 2017
The integration of biomaterials and understanding of vascular biology has led to the development of perfusable endothelialized flow models, which have been used as valuable tools to study the platelet–endothelium interface under shear.
Jevgenia Zilberman-Rudenko, Joanna L. Sylman, Kathleen S. Garland, Cristina Puy, Andrew D. Wong, Peter C. Searson, Owen J. T. McCarty   +6 more
doaj   +1 more source

Calculated VWF excess and VWF half-life in pregnancy. [PDF]

, 2014
Calculated VWF excess and VWF half-life in pregnancy.
Gayle T. Teramura (698015), Dominic W. Chung (126493), Hilary S. Gammill (345254), Barbara A. Konkle (698017), Kerry W. Lannert (698014), Jill M. Johnsen (698018), Danielle N. Drury-Stewart (698013), James C. Zimring (698016)   +7 more
core   +1 more source

Sialylation on O-linked glycans protects von Willebrand factor from macrophage galactose lectin-mediated clearance

Haematologica, 2021
Terminal sialylation determines the plasma half-life of von Willebrand factor (VWF). A role for macrophage galactose lectin (MGL) in regulating hyposialylated VWF clearance has recently been proposed.
Soracha E. Ward, Jamie M. O’Sullivan, Alan B. Moran, Daniel I. R. Spencer, Richard A. Gardner, Jyotika Sharma, Judicael Fazavana, Marco Monopoli, Thomas A.J. McKinnon, Alain Chion, Sandra Haberichter, James S. O’Donnell   +11 more
doaj   +1 more source