Results 51 to 60 of about 56,156 (204)

Frequency weightings of hand-transmitted vibration for predicting vibration-induced white finger

Scandinavian Journal of Work, Environment & Health, 2011
OBJECTIVE: The aim of this study was to investigate the performance of four frequency weightings for hand-transmitted vibration to predict the incidence of vibration-induced white finger (VWF).
Massimo Bovenzi, Iole Pinto, Francesco Picciolo, Marcella Mauro, Federico Ronchese   +4 more
doaj   +1 more source

Comparative analysis of TRPM8 gene and COPD markers expression in rat lungs following exposure to cigarette smoke and tobacco aerosol

Acta Biomedica Scientifica
Background. Chronic Obstructive Pulmonary Disease (COPD) remains a global medical and social problem. The ion channel TRPM8, a cold receptor, is known to be involved in the pathogenesis of the disease.
P. D. Timkin, M. A. Kiselev, D. A. Shapovalova, D. E. Naumov, P. M. Linskaya, E. A. Borodin   +5 more
doaj   +1 more source

A conformation-sensitive monoclonal antibody against the A2 domain of von Willebrand factor reduces its proteolysis by ADAMTS13. [PDF]

PLoS ONE, 2011
The size of von Willebrand factor (VWF), controlled by ADAMTS13-dependent proteolysis, is associated with its hemostatic activity. Many factors regulate ADAMTS13-dependent VWF proteolysis through their interaction with VWF.
Jingyu Zhang, Zhenni Ma, Ningzheng Dong, Fang Liu, Jian Su, Yiming Zhao, Fei Shen, Anyou Wang, Changgeng Ruan   +8 more
doaj   +1 more source

Summary of 8 mAbs to VWF and their effects on VWF proteolysis by ADAMTS13. [PDF]

, 2013
Summary of 8 mAbs to VWF and their effects on VWF proteolysis by ADAMTS13.
Ningzheng Dong (328283), Changgeng Ruan (328282), Jingyu Zhang (256203), Yiming Zhao (348349), Zhenni Ma (328280), Jian Su (86223), Anyou Wang (281729), Fang Liu (13271), Fei Shen (348351)   +8 more
core   +1 more source

A rat model of severe VWD by elimination of the VWF gene using CRISPR/Cas9

Research and Practice in Thrombosis and Haemostasis, 2020
Background Von Willebrand Disease (VWD) is the most common inherited bleeding disorder, caused by quantitative and qualitative changes in von Willebrand factor (VWF).
Jessica Garcia, Veronica H. Flood, Sandra L. Haberichter, Scot A. Fahs, Jeremy G. Mattson, Aron M. Geurts, Mark Zogg, Hartmut Weiler, Qizhen Shi, Robert R. Montgomery   +9 more
doaj   +1 more source

Identification and functional analysis of a novel von Willebrand factor mutation in a family with type 2A von Willebrand disease. [PDF]

PLoS ONE, 2012
von Willebrand factor (VWF) is essential for normal hemostasis. VWF gene mutations cause the hemorrhagic von Willebrand disease (VWD). In this study, a 9-year-old boy was diagnosed as type 2A VWD, based on a history of abnormal bleeding, low plasma VWF ...
Jing Dong, Xiaojuan Zhao, Sensen Shi, Zhenni Ma, Meng Liu, Qingyu Wu, Changgeng Ruan, Ningzheng Dong   +7 more
doaj   +1 more source

Staphylococcus aureus vWF-binding protein triggers a strong interaction between clumping factor A and host vWF [PDF]

, 2021
The Staphylococcus aureus cell wall-anchored adhesin ClfA binds to the very large blood circulating protein, von Willebrand factor (vWF) via vWF-binding protein (vWbp), a secreted protein that does not bind the cell wall covalently. Here we perform force
Marion Mathelié-Guinlet, Dominique Missiakas, Mathelie-Guinlet, Marion, Felipe Viela, Missiakas, Dominique, Viela Bovio, Felipe, Pietro Speziale, Pietrocola, Giampiero, Speziale, Pietro, Giampiero Pietrocola, Yves F Dufrêne, Viljoen, Albertus, Albertus Viljoen, Dufrêne, Yves   +13 more
core   +2 more sources

Binding of recombinant full-length and truncated fH molecules to VWF and VWF-A2. [PDF]

, 2013
(A) Recombinant GST VWF-A2 protein (100 nM) was mixed with recombinant full-length or truncated fH (30 nM) and precipitated using glutathione agarose beads.
Vahid Afshar-Kharghan (450560), Michael H. Kroll (450559), Jing-Fei Dong (450558), Miguel A. Cruz (368558), Naresh Pemmaraju (450557), Hangoc Vu (450556), Shuju Feng (450555), Xiaowen Liang (373131), Zhou Zhou (154603)   +8 more
core   +1 more source

Platelet reduction under hypoxia associated with GPIbα-vWF [PDF]

, 2023
Changes of platelet parameters in rats under chronic hypoxia;The changes of megakaryocyte number in bone marrow and lung tissue sections; The change of reticulated platelet proportion and platelet apoptosis; Effects of different oxygen concentrations on ...
Zhuoya Wang (16634874), Tana Wuren (16711770)   +1 more
core   +1 more source

Elevated Plasma von Willebrand Factor Antigen and Activity Levels Are Associated With the Severity of Coronary Stenosis

Clinical and Applied Thrombosis/Hemostasis, 2020
von Willebrand factor (VWF) acts as a bridge between platelets and the subendothelial matrix following vessel damage and plays a vital role in coronary artery disease (CAD).
Bin Yan MS, Qi Wang MS, Weipeng Du BS, Suping Zhai BS, Chaoyang Gou MS, Tianxi Hu BS, Lijun Xia PhD, Changgeng Ruan PhD, Yiming Zhao PhD   +8 more
doaj   +1 more source