Results 41 to 50 of about 56,156 (204)

Application of microfluidic devices in studies of thrombosis and hemostasis

open access: yesPlatelets, 2017
Due to the importance of fluid flow during thrombotic episodes, it is quite appropriate to study clotting and bleeding processes in devices that have well-defined fluid shear environments.
Changjie Zhang, Sriram Neelamegham
doaj   +1 more source

VWF, WM, and angiogenesis: is there a link? [PDF]

open access: yesBlood, 2012
In this issue of Blood , Hivert et al systematically examine the acquired reduction of von Willebrand factor (VWF) activity in patients with Waldenstrom macroglobulinemia (WM), but, surprisingly, they found that the high levels of VWF were a significant independent adverse prognostic factor.[1 ...
Kastritis, Efstathios   +1 more
openaire   +5 more sources

Mature vWF, smooth muscle actin, and vWF precursor protein expression in human small vessel disease. [PDF]

open access: yes, 2013
The same CADASIL cortical brain artery was examined by immunohistochemistry for mature vWF (A), smooth muscle actin (B), and vWF-pp (C). This vessel demonstrated transmural staining for mature vWF, subendothelial reactivity for SMA, and intimal-specific ...
He Meng (33363)   +3 more
core   +1 more source

Enhanced VWF biosynthesis and elevated plasma VWF due to a natural variant in the murine Vwf gene

open access: yesBlood, 2006
Abstract Both genetic and environmental influences contribute to the wide variation in plasma von Willebrand factor (VWF) levels observed in humans. Inbred mouse strains also have highly variable plasma VWF levels, providing a convenient model in which to study genetic modifiers of VWF.
Heidi L, Lemmerhirt   +5 more
openaire   +3 more sources

Identification of intracellular VWF. [PDF]

open access: yes, 2013
(A) ELISA assay showing reactivity of different antibodies to VWF. VWF was allowed to bind collagen coated wells and antibodies raised against ADAMTS13 (BL154G, Wh2-22-1A and Wh2-11-1) [35], VWF (MO616, A0082 and AXL205) or the anti-V5 (V5) as well as ...
Tanvi Gupta (371279)   +11 more
core   +1 more source

Viral inactivation in von Willebrand factor preparations via UVC irradiation: an experimental approach

open access: yesZhongguo shuxue zazhi
[Objective] To evaluate the efficacy of ultraviolet-C (UVC) irradiation in inactivating porcine parvovirus (PPV), encephalomyocarditis virus (EMCV), pseudorabies virus (PRV) and vesicular stomatitis virus (VSV) within von Willebrand factor (vWF ...
ZHANG Yalu   +3 more
doaj   +1 more source

Diagnostic Value of Measuring Platelet Von Willebrand Factor in Von Willebrand Disease. [PDF]

open access: yesPLoS ONE, 2016
Von Willebrand disease (VWD) may be caused by an impaired von Willebrand factor (VWF) synthesis, its increased clearance or abnormal function, or combinations of these factors.
Alessandra Casonato   +5 more
doaj   +1 more source

Complex changes in von Willebrand factor-associated parameters are acquired during uncomplicated pregnancy. [PDF]

open access: yesPLoS ONE, 2014
BACKGROUND:The coagulation protein von Willebrand Factor (VWF) is known to be elevated in pregnancy. However, the timing and nature of changes in VWF and associated parameters throughout pregnancy are not well understood.
Danielle N Drury-Stewart   +7 more
doaj   +1 more source

Factor H binds to VWF. [PDF]

open access: yes, 2013
(A) Purified VWF (20 nM) was incubated with different concentrations of fH (30, 60 nM) and immunoprecipitated (IP) using anti-VWF antibody or control IgG. VWF co-precipitated proteins were immunoblotted using anti-fH antibody.
Vahid Afshar-Kharghan (450560)   +8 more
core   +1 more source

ADAMTS13 Deficiency Worsens Colitis and Exogenous ADAMTS13 Administration Decreases Colitis Severity in Mice

open access: yesTH Open, 2017
Background Inflammatory bowel disease (IBD) affects 1.6 million people in the United States. IBD is associated with an increased risk of thrombosis, which rises with disease activity.
Naamah L. Zitomersky   +7 more
doaj   +1 more source

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