Results 141 to 150 of about 17,893 (237)
Shared Decision‐Making in Haemophilia Involves More Treatment Differentiators in 2026
Haemophilia, EarlyView.ABSTRACT Introduction Shared decision‐making regarding treatment choice in haemophilia care has become increasingly more complex and essential due to the availability of several innovative therapeutics that are characterized by their own advantages and limitations, which need to be tailored to individual patient needs.
Quentin Van Thillo +2 more
wiley +1 more source
Stul polymorphisms in the vWF gene [PDF]
Nucleic Acids Research, 1990 A, Inbal, R I, Handin
openaire +2 more sources
Haemophilia, EarlyView.Abstract Background Coagulation testing in persons with hemophilia A (PwHA) is required for diagnosis, monitoring replacement therapy, assessment of adherence, and detection of inhibitors. However, data on testing practices are limited, and alignment with guideline recommendations is unclear.
A. P. Bavinck +4 more
wiley +1 more source
ICSH Guidance on Bone Marrow Examination and Reporting
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Examination of the bone marrow (BM) remains fundamental to the diagnosis, classification, prognostication, and monitoring of hematolymphoid and other disorders affecting blood cell production. Since publication of the International Council for Standardization in Haematology (ICSH) guideline in 2008, advances in diagnostic technologies, disease
Wendy N. Erber +6 more
wiley +1 more source
C‐type cyclin CycC1;1 delays leaf senescence by interacting with and inhibiting MYC2 in Arabidopsis
Journal of Integrative Plant Biology, EarlyView.The C‐type cyclin CycC1;1 interacts with MYC2 and MED25 to block their association and RNA polymerase II recruitment, thereby repressing senescence‐associated gene expression and delaying leaf senescence in Arabidopsis. Unlike jasmonic acid‐inducible JAZ repressors, CycC1;1 operates independently of jasmonic acid signaling, representing an ...
Cai‐Yi Liao +9 more
wiley +1 more source
Genetic Susceptibility to Periodontitis
Journal of Periodontal Research, EarlyView.Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley +1 more source
The Role of Oxidative Stress in Periodontitis
Journal of Periodontal Research, EarlyView.Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon +3 more
wiley +1 more source
Plasma ADAMTS13 activity in healthy dogs and dogs with chronic enteropathy
Journal of Small Animal Practice, EarlyView.Objectives A disintegrin and metalloproteinase with thrombospondin type 1 motif, member 13 is a von Willebrand factor cleaving enzyme that is associated with prothrombotic/hypercoagulable states in humans. In people, A disintegrin and metalloproteinase with thrombospondin type 1 motif, member 13 activity is reduced with inflammatory bowel disease ...
S. I. Barth +4 more
wiley +1 more source
Molecular Oral Microbiology, EarlyView.Abstract Orthotopic allograft transplantation (OAT) is a significant approach to addressing organ failure. However, persistent immune responses to the allograft affect chronic rejection, which induces OAT vasculopathy (OATV) and organ failure. Porphyromonas gingivalis can infiltrate remote organs via the bloodstream, thereby intensifying the severity ...
Chien‐Sung Tsai +7 more
wiley +1 more source