Results 91 to 100 of about 60,736 (289)

Factor H binds to VWF.

open access: yes, 2013
(A) Purified VWF (20 nM) was incubated with different concentrations of fH (30, 60 nM) and immunoprecipitated (IP) using anti-VWF antibody or control IgG. VWF co-precipitated proteins were immunoblotted using anti-fH antibody.
Vahid Afshar-Kharghan (450560)   +8 more
core   +1 more source

Comparative Transcriptional Profiling of Key Macrophage and Fibroblast Subpopulations in Rheumatoid Arthritis–Associated Lung Disease

open access: yesArthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis (RA) often involves extra‐articular complications, including interstitial lung disease (ILD) and/or pulmonary nodules. Transcriptomic profiling of lung tissue provides the opportunity to directly assess cell‐specific gene expression and corresponding pathway activation in different types of rheumatoid lung disease ...
Tracy Tabib   +8 more
wiley   +1 more source

O-glycan determinants regulate VWF trafficking to Weibel-Palade bodies. [PDF]

open access: yes
Von Willebrand factor (VWF) undergoes complex post-translational modification within endothelial cells (EC) prior to secretion. This includes significant N- and O-linked glycosylation.
Petra E Bürgisser (18770413)   +7 more
core   +4 more sources

Mechanism study of an articular cartilage repair material and its forward‐looking test for space medicine

open access: yesBMEMat, EarlyView.
The regeneration process following dLhCG engraftment progressed through four distinct and interconnected stages. dLhCG maintained its regenerative efficacy after 6 months of cosmic exposure, supporting its potential application in space medicine.
Xu Hu   +8 more
wiley   +1 more source

Value of vWF-related indicators in the diagnosis of liver cirrhosis progression in patients with hepatitis B [PDF]

open access: yesZhenduanxue lilun yu shijian
Objective To evaluate the correlation between von Willebrand factor (vWF) and its related indicators and the progression of liver cirrhosis in patients with hepatitis B and explore the diagnostic value of vWF-related indicators in assisting the diagnosis
YANG Mingkang, LIU Yu, XU Guanqun, WANG Jianbiao, WANG Xuefeng, LIANG Qian
doaj   +1 more source

Innovation of plant‐derived extracellular vesicles and interdisciplinary research: From discovery to biomedical applications

open access: yesBMEMat, EarlyView.
Plant‐derived extracellular vesicles offer numerous advantages and are regarded as highly promising candidates in the field of biomedicine. Abstract Extracellular vesicles (EVs) are double‐membrane vesicular structures that can be secreted by nearly all living cells.
Zilin Li   +6 more
wiley   +1 more source

Von Willebrand Factor and ADAMTS13 in COVID-19 and Beyond: A Question of Balance

open access: yesEuropean Medical Journal Nephrology, 2021
von Willebrand factor (VWF) is a large, adhesive, multimeric protein involved in haemostasis. The larger the size (or number of VWF multimers), the greater the functionality of the protein. A deficiency or defect in VWF can lead to von Willebrand disease
Emmanuel J Favaloro   +2 more
doaj  

Reduced survival of type 2B von Willebrand factor, irrespective of large multimer representation or thrombocytopenia

open access: yesHaematologica, 2010
Background Type 2B von Willebrand factor (VWF) is characterized by gain of function mutations in the A1 domain inducing a greater affinity for platelet GPIb, possibly associated with the disappearance of large VWF multimers and thrombocytopenia.Design ...
Alessandra Casonato   +7 more
doaj   +1 more source

Binding of recombinant full-length and truncated fH molecules to VWF and VWF-A2.

open access: yes, 2013
(A) Recombinant GST VWF-A2 protein (100 nM) was mixed with recombinant full-length or truncated fH (30 nM) and precipitated using glutathione agarose beads.
Vahid Afshar-Kharghan (450560)   +8 more
core   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia   +2 more
wiley   +1 more source

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